Evidence map›Paper›PMID 31383744›Full record

ArticleInfection and immunity2019

Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells.

Jerry Z Xu, Ramesh Kumar, Haoli Gong, Luyao Liu, Nicole Ramos-Solis, Yujing Li, Wilbert A Derbigny

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Journal of Cancer · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jerry Z Xu *Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Ramesh Kumar *Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Haoli GongXiangya Second Hospital, Central South University, Changsha, Hunan Province, People's Republic of China.
Luyao LiuXiangya Second Hospital, Central South University, Changsha, Hunan Province, People's Republic of China.
Nicole Ramos-SolisDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Yujing LiDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Wilbert A DerbignyDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA wderbign@iupui.edu.ORCID 0000-0002-8250-6261
Indiana University School of MedicineCentral South University · CN

Funding

IPREP Supplemental: Physical Activity, Mental Health, and ResiliencyR25GM109432 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI BAHAMONDE, RAFAEL, ROPER, RANDALL J · 2014 to 2024
$4.1M
The role of TLR3 signaling in Chlamydia caused urogenital pathologyR01AI104944 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI DERBIGNY, WILBERT A · 2014 to 2017
$1.5M
NIAID NIH HHS R01 AI104944NIGMS NIH HHS R25 GM109432
6 · The paper itself

Abstract

Reproductive tract pathology caused by

Indexed as

B-Cell Activating FactorCell Line, TransformedChemokine CCL5Chlamydia trachomatisCytokine Receptor gp130Epithelial CellsFallopian TubesFemaleGene DeletionGene Expression RegulationHeLa CellsHost-Pathogen InteractionsHumansInterferon-gammaInterferon LambdaInterleukin-6B-Cell Activating FactorCCL5 protein, humanChemokine CCL5Cytokine Receptor gp130IFNG protein, humanIL6 protein, humanIL6R protein, humanInterferon-gammaInterferon Lambdainterferon-lambda, humanInterleukin-6InterleukinsMatrix Metalloproteinase 1MMP1 protein, humanReceptors, Interleukin-6TLR3 protein, humanTNFSF13B protein, humanToll-Like Receptor 3Chlamydia trachomatisepithelial cellsinflammationoviductsTLR3

Identifiers

PMID31383744
PMCPMC6759307
OpenAlexW2965845175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.