Evidence map›Paper›PMID 31383689›Full record

ArticleDisease models & mechanisms2019

Interactions among ryanodine receptor isotypes contribute to muscle fiber type development and function.

Alexis A Chagovetz, Dana Klatt Shaw, Erin Ritchie, Kazuyuki Hoshijima, David J Grunwald

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The RyR-like-FKBP12-PKA Complex Regulates Intracellular CaInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alexis A ChagovetzDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Dana Klatt ShawDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Erin RitchieDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Kazuyuki HoshijimaDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
David J GrunwaldDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA grunwald@genetics.utah.edu.ORCID 0000-0002-6784-6647
University of Utah · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007491 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI James Alan Gagnon, Kristen M Kwan · 1995 to 2026
$8.0M
A Toolkit for Gene-Targeting in ZebrafishR01HD081950 · NICHD · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J. · 2014 to 2018
$2.0M
Role of Intracellular Calcium Release in Hedgehog Growth Factor SignalingR21HD065169 · NICHD · UNIVERSITY OF UTAH · PI GRUNWALD, DAVID J. · 2010 to 2011
$400k
Mechanism by which SepN modulates function of the RyR calcium release channelR03NS071415 · NINDS · UNIVERSITY OF UTAH · PI ABRAMSON, JONATHAN J, GRUNWALD, DAVID J. · 2010 to 2011
$153k
NCI NIH HHS P30 CA042014NICHD NIH HHS R01 HD081950NICHD NIH HHS R21 HD065169NICHD NIH HHS T32 HD007491NINDS NIH HHS R03 NS071415
6 · The paper itself

Abstract

Mutations affecting ryanodine receptor (RyR) calcium release channels commonly underlie congenital myopathies. Although these channels are known principally for their essential roles in muscle contractility, mutations in the human

Indexed as

AllelesAnimalsBehavior, AnimalCalcium SignalingEmbryo, NonmammalianFaceMorphogenesisMuscle ContractionMuscle Fibers, SkeletalMutationProtein BindingReflex, StartleRyanodine Receptor Calcium Release ChannelSkullSwimmingZebrafishRyanodine Receptor Calcium Release ChannelZebrafish ProteinsCongenital myopathyMuscle developmentMuscle functionRyanodine receptorsZebrafish disease model

Identifiers

PMID31383689
PMCPMC6906632
OpenAlexW2965963804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.