Evidence map›Paper›PMID 31383659›Full record

ArticleAntimicrobial agents and chemotherapy2019

Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone.

Jorge Arca-Suárez, Pablo Fraile-Ribot, Juan Carlos Vázquez-Ucha, Gabriel Cabot, Marta Martínez-Guitián, Emilio Lence, Concepción González-Bello, Alejandro Beceiro, Manuel Rodríguez-Iglesias, Fátima Galán-Sánchez and 2 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. L2 β-lactamase contributes to ceftolozane-tazobactam resistance inAntimicrobial agents and chemotherapy · 2026
    Article
  2. Antimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. A novel mechanism of ceftolozane-tazobactam resistance inbioRxiv : the preprint server for biology · 2026
    Article
  5. Antibiotic-ResistantMicroorganisms · 2025
    Review
  6. High-riskHeliyon · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. New Drugs for the Treatment ofAntibiotics (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. New Carbapenemase Inhibitors: Clearing the Way for the β-Lactams.International journal of molecular sciences · 2020
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Jorge Arca-SuárezServicio de Microbiología-Instituto de Investigación Biomédica, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Pablo Fraile-RibotServicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears, Palma de Mallorca, Spain.
Juan Carlos Vázquez-UchaServicio de Microbiología-Instituto de Investigación Biomédica, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Gabriel CabotServicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears, Palma de Mallorca, Spain.ORCID 0000-0002-6452-9945
Marta Martínez-GuitiánServicio de Microbiología-Instituto de Investigación Biomédica, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Emilio LenceCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Concepción González-BelloCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Alejandro BeceiroServicio de Microbiología-Instituto de Investigación Biomédica, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain Alejandro.Beceiro.Casas@sergas.es.
Manuel Rodríguez-IglesiasServicio de Microbiología, Hospital Universitario Puerta del Mar, Instituto de Investigación e Innovación Biomédica de Cádiz, Cádiz, Spain.
Fátima Galán-Sánchez *Servicio de Microbiología, Hospital Universitario Puerta del Mar, Instituto de Investigación e Innovación Biomédica de Cádiz, Cádiz, Spain.
Germán Bou *Servicio de Microbiología-Instituto de Investigación Biomédica, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Antonio Oliver *Servicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears, Palma de Mallorca, Spain.ORCID 0000-0001-9327-1894
Complexo Hospitalario Universitario A Coruña · ESHospital Universitario Son Espases · ESUniversidad de Cádiz · ESUniversidade de Santiago de Compostela · ESBiomedical Research and Innovation Institute of Cadiz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selection of extended-spectrum mutations in narrow-spectrum oxacillinases (e.g., OXA-2 and OXA-10) is an emerging mechanism for development of

Indexed as

Aged, 80 and overAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesCeftazidimeCephalosporinsDrug CombinationsHumansKineticsMicrobial Sensitivity TestsPseudomonas aeruginosaPseudomonas InfectionsTazobactamWhole Genome SequencingAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo Compoundsbeta-LactamasesCeftazidimeceftolozane, tazobactam drug combinationCephalosporinsDrug CombinationsTazobactamantimicrobial resistanceceftazidime-avibactamceftolozane-tazobactamclass D beta-lactamaseOXAPseudomonas aeruginosa

Identifiers

PMID31383659
PMCPMC6761516
OpenAlexW2964602628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.