Evidence map›Paper›PMID 31383654›Full record

ArticleAntimicrobial agents and chemotherapy2019

Resistance and Heteroresistance to Colistin in Pseudomonas aeruginosa Isolates from Wenzhou, China.

Jie Lin, Chunquan Xu, Renchi Fang, Jianming Cao, Xiucai Zhang, Yajie Zhao, Guofeng Dong, Yao Sun, Tieli Zhou

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. High prevalence of colistin heteroresistance in Pseudomonas aeruginosa bloodstream isolates and associated clinical factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Antibiotic resistance mechanisms and global resistance patterns of Pseudomonas aeruginosa in microbial keratitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Article
  6. Article
  7. Article
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  9. Polymyxin heteroresistance inJournal of medical microbiology · 2026
    Article
  10. UnderstandingMicroorganisms · 2026
    Review
  11. Genotype Versus Phenotype in Pandrug-ResistantClinical medicine insights. Case reports · 2026
    Article
  12. An Investigation of Colistin Heteroresistance inBioMed research international · 2026
    Article
  13. Article
  14. Review
  15. Detection of Colistin Heteroresistance in Carbapenem-ResistantInternational journal of microbiology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie Lin *Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Chunquan Xu *Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Renchi FangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Jianming CaoDepartment of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China wzcjming@163.com wyztli@163.com.
Xiucai ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Yajie ZhaoDepartment of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Guofeng DongDepartment of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Yao SunDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Tieli ZhouDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China wzcjming@163.com wyztli@163.com.
Wenzhou Medical University · CNFirst Affiliated Hospital of Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal was to investigate the mechanisms of colistin resistance and heteroresistance in

Indexed as

Anti-Bacterial AgentsBacterial ProteinsChinaColistinDrug Resistance, Multiple, BacterialElectrophoresis, Gel, Pulsed-FieldGene Expression Regulation, BacterialHumansLipid AMicrobial Sensitivity TestsMultilocus Sequence TypingMutationPseudomonas aeruginosaPseudomonas InfectionsRepressor ProteinsTranscription FactorsAnti-Bacterial AgentsBacterial ProteinsColistinLipid AParR protein, bacteriaPhoP protein, BacteriapmrA protein, BacteriaPmrB protein, bacteriaRepressor ProteinsTranscription Factorscolistinheteroresistancelipid A modificationmolecular mechanismsPseudomonas aeruginosaresistance

Identifiers

PMID31383654
PMCPMC6761505
OpenAlexW2965819651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.