Evidence map›Paper›PMID 31383635›Full record

ReviewDisease models & mechanisms2019

Disease modelling in human organoids.

Madeline A Lancaster, Meritxell Huch

Open access · goldAbstract readReview
In one paragraph

Review in Disease models & mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 208 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
208citing papers in PubMed, 4 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

208 citing papers in PubMed, 4 syntheses or guidelines pooled it, 370 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Advances in Engineering Human Tissue Models.Frontiers in bioengineering and biotechnology · 2020
    Pooled it
  5. Article
  6. Patient-derived organoids in gynaecological cancers: emerging tools for therapy and disease modelling.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. [Advances in the construction and application of a novel liver organoid model for hepatitis B virus infection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article

148 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Madeline A LancasterMRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK mlancast@mrc-lmb.cam.ac.uk m.huch@gurdon.cam.ac.uk huch@mpi-cbg.de.ORCID 0000-0003-2324-8853
Meritxell HuchThe Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK mlancast@mrc-lmb.cam.ac.uk m.huch@gurdon.cam.ac.uk huch@mpi-cbg.de.ORCID 0000-0002-1545-5265
MRC Laboratory of Molecular Biology · GBUniversity of Cambridge · GB

Funding

Medical Research Council MC_UP_1201/9Wellcome TrustWellcome Trust 104151/Z/14/Z
6 · The paper itself

Abstract

The past decade has seen an explosion in the field of

Indexed as

Models, BiologicalAnimalsHumansOrganoidsEmbryonic developmentIn vitroRegenerative medicineStem cells

Identifiers

PMID31383635
PMCPMC6679380
OpenAlexW2964772567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.