Evidence map›Paper›PMID 31383275›Full record

ReviewGastroenterology clinics of North America2019

Gut-Brain Interactions: Implications for a Role of the Gut Microbiota in the Treatment and Prognosis of Anorexia Nervosa and Comparison to Type I Diabetes.

Daria Igudesman, Megan Sweeney, Ian M Carroll, Elizabeth J Mayer-Davis, Cynthia M Bulik

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Gastroenterology clinics of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. The human microbiome in disease and pathology.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Daria IgudesmanDepartment of Nutrition, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC 27599, USA.
Megan SweeneyDepartment of Nutrition, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC 27599, USA.
Ian M CarrollDepartment of Nutrition, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC 27599, USA.
Elizabeth J Mayer-DavisDepartment of Nutrition, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC 27599, USA.
Cynthia M BulikDepartment of Nutrition, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC 27599, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC 27599, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Electronic address: cbulik@med.unc.edu.
University of North Carolina at Chapel Hill · USKarolinska Institutet · SE

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)SEARCH for Diabetes in Youth Cohort StudyUC4DK108173 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DAGOSTINO, RALPH B. · 2015 to 2016
$14.8M
FL3X: An Adaptive Intervention to Improve Outcomes for Youth with Type 1 DiabetesUC4DK101132 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAAHS, DAVID MATTHEW, MAYER-DAVIS, ELIZABETH J · 2013 to 2013
$6.9M
SEARCH Nutrition Ancillary Study 2R01DK077949 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAYER-DAVIS, ELIZABETH J, THE, NATALIE · 2008 to 2017
$5.4M
Microbiome-mediated weight, anxiety, and stress dysregulation in anorexia nervosaR01MH105684 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARROLL, IAN MICHAEL · 2015 to 2019
$3.9M
Reducing risk factors for type 2 diabetes in American Indian youth: Tribal Turning PointR01DK115434 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DABELEA, DANA, SAUDER, KATHERINE A. · 2017 to 2021
$2.8M
Accelerating Solutions to Optimize Glycemic Control and Weight Management In Young Adults with Type 1 DiabetesDP3DK113358 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAAHS, DAVID MATTHEW, MAYER-DAVIS, ELIZABETH J · 2017 to 2017
$1.9M
SEARCH for Diabetes in Youth Registry Study, Phase 4: Carolina Center (Component A)U18DP006138 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAYER-DAVIS, ELIZABETH J · 2015 to 2019
$1.9M
Sulfadoxine-Pyrimethamine IPTp in Malawi: Effects on the gut and vaginal microbiomesR21AI125800 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARROLL, IAN MICHAEL, MESHNICK, STEVEN RICHARD · 2016 to 2017
$418k
Premorbid metabolism and growth in anorexia nervosa: A genetically informed exploration of riskR21MH115397 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, MICALI, NADIA · 2017 to 2018
$362k
AHRQ HHS HHSA290201200008INCCDPHP CDC HHS U18 DP006138NIAID NIH HHS R21 AI125800NIDDK NIH HHS DP3 DK113358NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK077949NIDDK NIH HHS R01 DK115434NIDDK NIH HHS UC4 DK101132NIDDK NIH HHS UC4 DK108173NIMH NIH HHS R01 MH105684NIMH NIH HHS R21 MH115397
6 · The paper itself

Abstract

Anorexia nervosa has poor prognosis and treatment outcomes and is influenced by genetic, metabolic, and psychological factors. Gut microbes interact with gut physiology to influence metabolism and neurobiology, although potential therapeutic benefits remain unknown. Type 1 diabetes is linked to anorexia nervosa through energy dysregulation, which in both disease states is related to the gut microbiota, disordered eating, and genetics.

Indexed as

Anorexia NervosaBrainDiabetes Mellitus, Type 1Gastrointestinal MicrobiomeHumansPrognosisAnorexia nervosaDiabetesMetabolismMicrobiomeMicrobiota

Identifiers

PMID31383275
PMCPMC6686879
OpenAlexW2954894803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.