ArticleTrials2019
A prospective randomised controlled trial of operative versus non-operative management of fractures of the humeral diaphysis: the HUmeral Shaft Fracture FIXation (HU-FIX) Study protocol.
Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Randomised Controlled Trial of Operative Versus Nonoperative Management of Fractures of the Humeral Diaphysis
Scandinavian Humeral diAphyseal Fracture Trial - A Pragmatic Randomized Controlled Trial
Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Trial
- Chest wall soft tissue thickness is associated with humeral shaft non-union: A radiographic study.Shoulder & elbow · 2024Article
- A retrospective analysis of functional and radiographic outcomes of humeral shaft fractures treated operatively versus nonoperatively.JSES international · 2024Article
- A Scoring System for Predicting Nonunion After Intramedullary Nailing of Femoral Shaft Fractures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024Article
- Routine fixation of humeral shaft fractures is cost-effective : cost-utility analysis of 215 patients at a mean of five years following nonoperative management.Bone & joint open · 2022Article
- Article
- Treatment of Midshaft Humerus Fractures Using Early Functional Bracing: Results and Prognostic Factors.Cureus · 2021Article
- [Antegrade and retrograde nailing of humeral shaft fractures].Operative Orthopadie und Traumatologie · 2021Article
- Can We Stratify Quality and Cost for Older Patients With Proximal and Midshaft Humerus Fractures?Geriatric orthopaedic surgery & rehabilitation · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHumeral shaft fractures constitute around 1% of adult fractures in the UK, with an annual incidence of approximately 13 per 100,000 population. Historically, these injuries have been primarily managed non-operatively, with operative fixation reserved for specific indications. Although some recent retrospective studies have suggested there are potential benefits of operative fixation over humeral bracing, there is a deficiency in level 1 evidence to support operative management as the primary treatment for humeral shaft fractures. METHODS/
designThis single-centre prospective randomised controlled trial aims to recruit 70 adult patients with an isolated closed fracture of the humeral diaphysis into one of two treatment arms: operative (n = 35) or non-operative (n = 35). The operative arm will undergo open reduction and internal fixation (ORIF) of the fracture using a standard fixation technique (plate and screws). The non-operative arm will be fitted with a prefabricated humeral brace until fracture union. All patients will be followed up for 1 year post-intervention. The primary outcome measure will be the Disabilities of the Arm, Shoulder and Hand (DASH) score at 3 months post-intervention. Secondary outcome measures will include pain, treatment complications, return to work or sporting activities, shoulder and elbow range of motion, radiographic assessment, EuroQol (EQ-5D) Health Outcome score and 12-item Short Form (SF-12) Health Survey score. A health economic analysis will be performed to compare the cost implications of each treatment strategy. DISCUSSION: This randomised controlled trial will provide level 1 evidence comparing a standard ORIF technique against functional bracing for isolated closed humeral shaft fractures. The investigators hope that the study results will assist surgeons in their decision-making when managing patients with these injuries.
trial registrationClinicalTrials.gov, NCT03689335 . Registered on 28 September 2018 (retrospectively).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.