ArticleBMC plant biology2019
Circular RNA profiling of the rice photo-thermosensitive genic male sterile line Wuxiang S reveals circRNA involved in the fertility transition.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A comprehensive landscape of theFrontiers in plant science · 2026Article
- MicroRNAs-mediated heat stress regulations in plants: Mechanisms and targets.The plant genome · 2025Review
- The circular RNA circANK suppresses rice resistance to bacterial blight by inhibiting microRNA398b-mediated defense.The Plant cell · 2025Article
- Review
- Dynamics and regulatory role of circRNAs in Asian honey bee larvae following fungal infection.Applied microbiology and biotechnology · 2024Article
- Defense Regulatory Network Associated with circRNA in Rice in Response to Brown Planthopper Infestation.Plants (Basel, Switzerland) · 2024Article
- Identification and characterization of circular RNAs involved in the fertility stability of cotton CMS-D2 restorer line under heat stress.BMC plant biology · 2024Article
- CircPCBL: Identification of Plant CircRNAs with a CNN-BiGRU-GLT Model.Plants (Basel, Switzerland) · 2023Article
- Identification, biogenesis, function, and mechanism of action of circular RNAs in plants.Plant communications · 2023Review
- Non-coding RNA expression analysis revealed the molecular mechanism of flag leaf heterosis in inter-subspecific hybrid rice.Frontiers in plant science · 2022Article
- Opportunities and Challenges of Predictive Approaches for the Non-coding RNA in Plants.Frontiers in plant science · 2022Article
- Combined analysis of transcriptome and metabolome reveals that sugar, lipid, and phenylpropane metabolism are essential for male fertility in temperature-induced male sterile rice.Frontiers in plant science · 2022Article
- Role of long non-coding RNAs in rice reproductive development.Frontiers in plant science · 2022Review
- Circular RNAs Repertoire and Expression Profile duringInternational journal of molecular sciences · 2021Article
- Jasmonic Acid Plays a Pivotal Role in Pollen Development and Fertility Regulation in Different Types of P(T)GMS Rice Lines.International journal of molecular sciences · 2021Article
- Systematic identification and characterization of circular RNAs involved in flag leaf senescence of rice.Planta · 2021Article
- Identification of Circular RNAs by Multiple Displacement Amplification and Their Involvement in Plant Development.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Identification and Characterization of circRNAs Responsive to Methyl Jasmonate inInternational journal of molecular sciences · 2020Article
- Genome-Wide Identification of lncRNAs Involved in Fertility Transition in the Photo-Thermosensitive Genic Male Sterile Rice Line Wuxiang S.Frontiers in plant science · 2020Article
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Abstract
backgroundCircular RNAs (circRNAs) are known to play an important role in the regulation of gene expression in eukaryotes. Photo-thermosensitive genic male sterile (PTGMS) is a very important germplasm resource in two-line hybrid rice breeding. Although many circRNAs have been identified in rice (Oryza sativa L.), little is known about the biological roles of circRNAs in the fertility transition of the PTGMS rice line.
resultsIn the present study, RNA-sequencing libraries were constructed from the young panicles of the Wuxiang S sterile line rice (WXS (S)) and its fertile line rice (WXS (F)) at three development stages with three biological replicates. A total of 9994 circRNAs were obtained in WXS rice based on high-throughput strand-specific RNA sequencing and bioinformatic approaches, of which 5305 were known circRNAs and 4689 were novel in rice. And 14 of 16 randomly selected circRNAs were experimentally validated with divergent primers. Our results showed that 186 circRNAs were significantly differentially expressed in WXS (F) compared with WXS (S), of which 97, 87 and 60 circRNAs were differentially expressed at the pollen mother cell (PMC) formation stage (P2), the meiosis stage (P3) and the microspore formation stage (P4), respectively. Fertility specific expression patterns of eight circRNAs were analysis by qRT-PCR. Gene ontology (GO) and KEGG pathway analysis of the parental genes of differentially expressed circRNAs (DECs) revealed that they mainly participated in various biological processes such as development, response to stimulation, hormonal regulation, and reproduction. Furthermore, 15 DECs were found to act as putative miRNA sponges to involved in fertility transition in PTGMS rice line.
conclusionIn the present study, the abundance and characteristics of circRNAs were investigated in the PTGMS rice line using bioinformatic approaches. Moreover, the expression patterns of circRNAs were different between WXS (F) and WXS (S). Our findings primarily revealed that circRNAs might be endogenous noncoding regulators of flower and pollen development, and were involved in the fertility transition in the PTGMS rice line, and guide the production and application of two-line hybrid rice.
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