Evidence map›Paper›PMID 31382656›Full record

ReviewInternational journal of molecular sciences2019

Periodontal Disease in Patients Receiving Dialysis.

Yasuyoshi Miyata, Yoko Obata, Yasushi Mochizuki, Mineaki Kitamura, Kensuke Mitsunari, Tomohiro Matsuo, Kojiro Ohba, Hiroshi Mukae, Tomoya Nishino, Atsutoshi Yoshimura and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  16. Role of connexin 43 in a rat model of periodontitis-induced renal injury.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yasuyoshi MiyataDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan. yasu-myt@nagasaki-u.ac.jp.ORCID 0000-0001-6272-6657
Yoko ObataDepartment of Nephrology, Nagasaki University Hospital, Nagasaki 852-8501, Japan.
Yasushi MochizukiDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Mineaki KitamuraDepartment of Nephrology, Nagasaki University Hospital, Nagasaki 852-8501, Japan.
Kensuke MitsunariDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Tomohiro MatsuoDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Kojiro OhbaDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.ORCID 0000-0003-2841-1998
Hiroshi MukaeDepartment of Respiratory Medicine, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8591, Japan.
Tomoya NishinoDepartment of Nephrology, Nagasaki University Hospital, Nagasaki 852-8501, Japan.
Atsutoshi YoshimuraDepartment of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.ORCID 0000-0002-5766-1286
Hideki SakaiDepartment of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
Nagasaki University · JPNagasaki University Hospital · JP

Funding

KAKENHI 16K15690
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is characterized by kidney damage with proteinuria, hematuria, and progressive loss of kidney function. The final stage of CKD is known as end-stage renal disease, which usually indicates that approximately 90% of normal renal function is lost, and necessitates renal replacement therapy for survival. The most widespread renal replacement therapy is dialysis, which includes peritoneal dialysis (PD) and hemodialysis (HD). However, despite the development of novel medical instruments and agents, both dialysis procedures have complications and disadvantages, such as cardiovascular disease due to excessive blood fluid and infections caused by impaired immunity. Periodontal disease is chronic inflammation induced by various pathogens and its frequency and severity in patients undergoing dialysis are higher compared to those in healthy individuals. Therefore, several investigators have paid special attention to the impact of periodontal disease on inflammation-, nutrient-, and bone metabolism-related markers; the immune system; and complications in patients undergoing dialysis. Furthermore, the influence of diabetes on the prevalence and severity of manifestations of periodontal disease, and the properties of saliva in HD patients with periodontitis have been reported. Conversely, there are few reviews discussing periodontal disease in patients with dialysis. In this review, we discuss the available studies and review the pathological roles and clinical significance of periodontal disease in patients receiving PD or HD. In addition, this review underlines the importance of oral health and adequate periodontal treatment to maintain quality of life and prolong survival in these patients.

Indexed as

Diabetes MellitusHumansKidney Failure, ChronicOral HealthPeriodontal DiseasesPeritoneal DialysisQuality of LifeRenal Dialysisdiabeteshemodialysisimmune responseperiodontal diseaseperitoneal dialysis

Identifiers

PMID31382656
PMCPMC6695931
OpenAlexW2965611301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.