Evidence map›Paper›PMID 31382613›Full record

ReviewCells2019

WNT Signaling in Disease.

Li Fang Ng, Prameet Kaur, Nawat Bunnag, Jahnavi Suresh, Isabelle Chiao Han Sung, Qian Hui Tan, Jan Gruber, Nicholas S Tolwinski

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 1 synthesis or guideline pooled it, 212 citations in OpenAlex.

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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Li Fang NgDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Prameet KaurDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Nawat BunnagDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Jahnavi SureshDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Isabelle Chiao Han SungDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Qian Hui TanDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Jan GruberDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore.
Nicholas S TolwinskiDivision of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore. Nicholas.tolwinski@yale-nus.edu.sg.
Yale-NUS College · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.

Indexed as

Wnt Signaling PathwayAgingAlzheimer DiseaseEmbryonic DevelopmentHumansMetabolic DiseasesNeoplasmsAlzheimer’s diseasecancermetabolic syndromeWNT

Identifiers

PMID31382613
PMCPMC6721652
OpenAlexW2964682226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.