ArticleMaterials (Basel, Switzerland)2019
Adhesive Cements That Bond Soft Tissue Ex Vivo.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Crosslinker-Free, Printable Alginate-Boronic Acid Hydrogel Adhesive with Enhanced Mechanical Performance for Soft Tissue Fixation.Molecules (Basel, Switzerland) · 2026Article
- Mechanical Evaluation of Commercially Available Fibrin Sealants for Cartilage Repair.Cartilage · 2024Article
- Nuclear Magnetic Resonance and Metadynamics Simulations Reveal the Atomistic Binding of l-Serine andChemistry of materials : a publication of the American Chemical Society · 2022Article
- Biodegradable and Biocompatible Adhesives for the Effective Stabilisation, Repair and Regeneration of Bone.Bioengineering (Basel, Switzerland) · 2022Review
- Refined Structures ofThe journal of physical chemistry. B · 2021Article
- Gluing Living Bone Using a Biomimetic Bioadhesive: From Initial Cut to Final Healing.Frontiers in bioengineering and biotechnology · 2021Article
- Synthesis of Phospho-Amino Acid Analogues as Tissue Adhesive Cement Additives.ACS central science · 2020Article
- In vivo safety assessment of a bio-inspired bone adhesive.Journal of materials science. Materials in medicine · 2020Article
- Phosphoserine Functionalized Cements Preserve Metastable Phases, and Reprecipitate Octacalcium Phosphate, Hydroxyapatite, Dicalcium Phosphate, and Amorphous Calcium Phosphate, during Degradation, In Vitro.Journal of functional biomaterials · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The aim of the present study was to evaluate the soft tissue bond strength of a newly developed, monomeric, biomimetic, tissue adhesive called phosphoserine modified cement (PMC). Two types of PMCs were evaluated using lap shear strength (LSS) testing, on porcine skin: a calcium metasilicate (CS1), and alpha tricalcium phosphate (αTCP) PMC. CS1 PCM bonded strongly to skin, reaching a peak LSS of 84, 132, and 154 KPa after curing for 0.5, 1.5, and 4 h, respectively. Cyanoacrylate and fibrin glues reached an LSS of 207 kPa and 33 kPa, respectively. αTCP PMCs reached a final LSS of ≈110 kPa. In soft tissues, stronger bond strengths were obtained with αTCP PMCs containing large amounts of amino acid (70-90 mol%), in contrast to prior studies in calcified tissues (30-50 mol%). When αTCP particle size was reduced by wet milling, and for CS1 PMCs, the strongest bonding was obtained with mole ratios of 30-50% phosphoserine. While PM-CPCs behave like stiff ceramics after setting, they bond to soft tissues, and warrant further investigation as tissue adhesives, particularly at the interface between hard and soft tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.