Evidence map›Paper›PMID 31382538›Full record

ArticleVaccines2019

Proteomic Analysis of Antigen 60 Complex of

Khayriyyah Mohd Hanafiah, Norsyahida Arifin, Paul R Sanders, Nurulhasanah Othman, Mary L Garcia, David A Anderson

Abstract read
In one paragraph

Article in Vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The Ubiquitination ofBiology · 2025
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khayriyyah Mohd HanafiahSchool of Biological Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia. kye@usm.my.
Norsyahida ArifinInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang 11800, Malaysia.
Paul R SandersLife Sciences, Macfarlane Burnet Institute, Melbourne, VIC 3004, Australia.
Nurulhasanah OthmanInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang 11800, Malaysia.
Mary L GarciaLife Sciences, Macfarlane Burnet Institute, Melbourne, VIC 3004, Australia.
David A AndersonLife Sciences, Macfarlane Burnet Institute, Melbourne, VIC 3004, Australia.

Funding

Australian Endeavour Research Fellowship 6036_2017Malaysian Ministry of Education 6711581Universiti Sains Malaysia Short Term Grant 6313319
6 · The paper itself

Abstract

Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) is a thermostable mycobacterial complex typically purified from Bacillus Calmette-Guérin (BCG) vaccine. A60 was historically evaluated for TB serodiagnostic and vaccine potential with variable findings. Despite containing immunogenic proteins, A60 has yet to be proteomically characterized. Here, commercial A60 was (1) trypsin-digested in-solution, analyzed by LC-MS/MS, searched against

Indexed as

BCGbiomarkersextracellular vesiclesmass spectrometryprotein–protein interactiontuberculosis

Identifiers

PMID31382538
PMCPMC6789874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.