Evidence map›Paper›PMID 31382475›Full record

ArticleInternational journal of environmental research and public health2019

Treatment with 3-Aminobenzamide Negates the Radiofrequency-Induced Adaptive Response in Two Cell Models.

Anna Sannino, Olga Zeni, Stefania Romeo, Maria Brigida Lioi, Maria Rosaria Scarfì

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna SanninoInstitute for Electromagnetic Sensing of the Environment (IREA), Italian National Research Council (CNR), 80124 Naples, Italy.
Olga ZeniInstitute for Electromagnetic Sensing of the Environment (IREA), Italian National Research Council (CNR), 80124 Naples, Italy.ORCID 0000-0002-2432-2384
Stefania RomeoInstitute for Electromagnetic Sensing of the Environment (IREA), Italian National Research Council (CNR), 80124 Naples, Italy.ORCID 0000-0002-9849-3637
Maria Brigida LioiDepartment of Science, University of Basilicata, 85100 Potenza, Italy.
Maria Rosaria ScarfìInstitute for Electromagnetic Sensing of the Environment (IREA), Italian National Research Council (CNR), 80124 Naples, Italy. scarfi.mr@irea.cnr.it.ORCID 0000-0002-9308-6928
Istituto per il Rilevamento Elettromagnetico dell'Ambiente · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In previous investigations, we demonstrated that pre-exposure of different cell cultures to radiofrequency fields can reduce the damage induced by genotoxic agents, an effect resembling the so-called adaptive response. In this study, we pre-exposed human peripheral blood lymphocytes and Chinese hamster lung fibroblast cell line to 1950 MHz, UMTS (Universal Mobile Telecommunication System) signal, for 20 h, and then treated cultures with Mitomycin-C. After confirming the induction of an adaptive response in terms of the reduction of micronuclei formation, we observed that such a response was negated by treatments with 3-aminobenzamide. Since 3-aminobenzamide is an inhibitor of poly (ADP-ribose) polymerase enzyme, which is involved in DNA repair, these results support the possible involvement of DNA repair mechanisms in radiofrequency-induced adaptive response.

Indexed as

Models, BiologicalRadio WavesAdaptation, PhysiologicalAnimalsBenzamidesCell LineCells, CulturedCricetinaeCricetulusDNA DamageDNA RepairHumansLymphocytesMicronuclei, Chromosome-DefectiveMitomycinPoly (ADP-Ribose) Polymerase-13-aminobenzamideBenzamidesMitomycinPARP1 protein, humanPoly (ADP-Ribose) Polymerase-13-aminobenzamideadaptive responsehuman lymphocytesmicronucleiradiofrequencyV79 cells

Identifiers

PMID31382475
PMCPMC6696271
OpenAlexW2964426361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.