Evidence map›Paper›PMID 31382449›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Ketogenic Diet and microRNAs Linked to Antioxidant Biochemical Homeostasis.

Roberto Cannataro, Maria Cristina Caroleo, Alessia Fazio, Chiara La Torre, Pierluigi Plastina, Luca Gallelli, Graziantonio Lauria, Erika Cione

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 56 citations in OpenAlex.

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  17. Mechanisms Contributing to the Comorbidity of COPD and Lung Cancer.International journal of molecular sciences · 2023
    Review
  18. Liver Damage and microRNAs: An Update.Current issues in molecular biology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Roberto CannataroGalaScreen Laboratories, Mater Domini Hospital 88100 Catanzaro and Department of Pharmacy, Health and Nutrition Sciences, University of Calabria, 87036 Rende (CS), Italy.
Maria Cristina CaroleoDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy.
Alessia FazioDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy.
Chiara La TorreDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy.
Pierluigi PlastinaDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy.
Luca GallelliClinical Pharmacology and Pharmacovigilance Operative Unit, Department of Health Science, University of Magna Graecia, Mater Domini Hospital Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902
Graziantonio LauriaDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy.
Erika CioneDepartment of Pharmacy, Health and Nutrition Sciences, University of Calabria, Via Pietro Bucci, 87036 Rende (CS), Italy. erika.cione@unical.it.
University of Calabria · ITAzienda Ospedaliero Universitario Mater Domini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, we demonstrated the capability of the ketogenic diet (KD) to influence the microRNA (miR) expression profile. Here, we report that KD is able to normalize miR expression in obese subjects when compared with lean subjects. By applying two different bioinformatics tools, we found that, amongst the miRs returning to comparable levels in lean subjects, four of them are linked to antioxidant biochemical pathways specifically, and the others are linked to both antioxidant and anti-inflammatory biochemical pathways. Of particular interest is the upregulation of hsa-miR-30a-5p, which correlates with the decrease of catalase expression protein in red blood cells.

Indexed as

catalaseketogenic dietmicroRNAs signature

Identifiers

PMID31382449
PMCPMC6719224
OpenAlexW2965477196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.