Evidence map›Paper›PMID 31382390›Full record

ArticlePharmaceutics2019

Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(l-histidine)-Based Multifunctional Micelles.

Li Jia, Nan Jia, Yan Gao, Haiyang Hu, Xiuli Zhao, Dawei Chen, Mingxi Qiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li JiaSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.ORCID 0000-0002-8687-7262
Nan JiaSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.
Yan GaoSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.
Haiyang HuSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.
Xiuli ZhaoSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.
Dawei ChenSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China.
Mingxi QiaoSchool of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, P.O. Box 42, Shenyang 110016, China. qiaomingxi@163.com.
Shenyang Pharmaceutical University · CN

Funding

National Natural Science Foundation of China 81573372
6 · The paper itself

Abstract

Even though the reversal of multi-drug resistance (MDR) by numerous nanoparticles has been extensively studied, limited success has been achieved. To overcome this barrier, we report a rationally-designed pH-sensitive micelle, in which doxorubicin (Dox) and resveratrol (Res) were co-loaded. The micelle was based on methoxy

Indexed as

MDRpH sensitive micellepoly(l-histidine)

Identifiers

PMID31382390
PMCPMC6723117
OpenAlexW2965254272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.