Evidence map›Paper›PMID 31382090›Full record

ArticleJournal of photochemistry and photobiology. B, Biology2019

Photobiomodulation combined with photodynamic therapy using ruthenium phthalocyanine complexes in A375 melanoma cells: Effects of nitric oxide generation and ATP production.

Laísa Bonafim Negri, Tassia Joi Martins, Roberto Santana da Silva, Michael R Hamblin

Abstract read
In one paragraph

Article in Journal of photochemistry and photobiology. B, Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Photosensitized co-generation of nitric oxide and singlet oxygen Enhanced toxicity against ovarian cancer cells.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laísa Bonafim NegriDepartamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo, Avenida do Cafe s/n, Ribeirão Preto, SP, Brazil.
Tassia Joi MartinsDepartamento de Química, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Roberto Santana da SilvaDepartamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo, Avenida do Cafe s/n, Ribeirão Preto, SP, Brazil; Departamento de Química, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP, Brazil; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address: silva@usp.br.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Dermatology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: hamblin@helix.mgh.harvard.edu.

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

Light irradiation has been used in clinical therapy for several decades. In this context, photobiomodulation (PBM) modulates signaling pathways via ROS, ATP, Ca

Indexed as

Adenosine TriphosphateCell Line, TumorCell SurvivalCoordination ComplexesHumansLightMelanomaNitric OxideOrganometallic CompoundsPhotochemotherapyPhotosensitizing AgentsSinglet OxygenAdenosine TriphosphateCoordination ComplexesNitric OxideOrganometallic CompoundsPhotosensitizing Agentsruthenium phthalocyanineSinglet OxygenLight irradiation therapyMetal-based drugNitrosyl ruthenium-phthalocyanine complexPhotobiomodulation

Identifiers

PMID31382090
PMCPMC6745525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.