Evidence map›Paper›PMID 31381861›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Tuberculosis Diagnosis in Children Using Xpert Ultra on Different Respiratory Specimens.

Heather J Zar, Lesley J Workman, Margaretha Prins, Linda J Bateman, Slindile P Mbhele, Cynthia B Whitman, Claudia M Denkinger, Mark P Nicol

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 10 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 10 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Pooled it
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  4. Diagnostic accuracy of Xpert MTB/RIF Ultra for detecting pulmonary tuberculosis and rifampicin resistance: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
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  7. Evaluating the efficacy of stool sample on Xpert MTB/RIF Ultra and its comparison with other sample types by meta-analysis for TB diagnostics.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Pooled it
  8. Diagnostic accuracy of Xpert ultra for childhood tuberculosis: A preliminary systematic review and meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Pooled it
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Heather J ZarDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit on Child and Adolescent Health and.ORCID 0000-0002-9046-759X
Lesley J WorkmanDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit on Child and Adolescent Health and.
Margaretha PrinsDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit on Child and Adolescent Health and.
Linda J BatemanDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit on Child and Adolescent Health and.
Slindile P MbheleDivision of Medical Microbiology, University of Cape Town, Cape Town, South Africa.
Cynthia B WhitmanDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit on Child and Adolescent Health and.
Claudia M DenkingerFoundation for Innovative New Diagnostics, Geneva, Switzerland.
Mark P NicolDivision of Medical Microbiology, University of Cape Town, Cape Town, South Africa.
South African Medical Research Council · ZAUniversity of Cape Town · ZAFIND · CH

Funding

Diagnosis of Tuberculosis in HIV-infected children & development of microbiologicR01HD058971 · NICHD · UNIVERSITY OF CAPE TOWN · PI ZAR, HEATHER JOY · 2008 to 2012
$2.2M
NICHD NIH HHS R01 HD058971
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAge FactorsChildChild, PreschoolFemaleHumansInfantMaleMolecular Diagnostic TechniquesMycobacterium tuberculosisSensitivity and SpecificitySouth AfricaSputumTime FactorsTuberculosis, Pulmonarychildinduced sputumnasopharyngeal aspiratetuberculosisXpert Ultra

Identifiers

PMID31381861
PMCPMC6909828
OpenAlexW2964664280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.