ArticlePloS one2019
High prevalence and diversity of extended-spectrum β-lactamase and emergence of OXA-48 producing Enterobacterales in wildlife in Catalonia.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Pooled it
- Frequency of Klebsiella spp. and Antimicrobial Resistance Patterns in Clinically Healthy Captive Night Monkeys (Aotus nancymaae) in the Peruvian Amazon.Journal of medical primatology · 2026Article
- Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids.Zoonoses and public health · 2026Article
- Occurrence of third-generation cephalosporin-resistant Escherichia coli in European hedgehogs (Erinaceus europaeus) from a wildlife rescue centre in Lombardy, Northern Italy.Veterinary research communications · 2026Article
- The Wildlife-Livestock Interface as a Bidirectional Pathway for the Spread of ESBL-ProducingAnimals : an open access journal from MDPI · 2026Review
- Antimicrobial resistance in wildlife: detection of β-lactam/carbapenem resistance genes in European hedgehogs (Erinaceus europaeus, Linnaeus 1758) in Italy.Veterinary research communications · 2026Article
- Virulome-resistome convergence in swine-associated multidrug-resistantFrontiers in veterinary science · 2026Article
- Article
- Reassessing the role of wild birds in the spread of antibiotic resistance: the white stork as a model species in studying populations from Central European river valley.Microbiology spectrum · 2025Article
- Looking for ESKAPE Bacteria: Occurrence and Phenotypic Antimicrobial Resistance Profiles in Wild Birds from Northern and Central Italy Sites.Antibiotics (Basel, Switzerland) · 2025Article
- Zoonotic Risks ofMicroorganisms · 2025Review
- Resisting the Final Line: Phenotypic Detection of Resistance to Last-Resort Antimicrobials in Gram-Negative Bacteria Isolated from Wild Birds in Northern Italy.Animals : an open access journal from MDPI · 2025Article
- Antimicrobial Resistance inAnimals : an open access journal from MDPI · 2025Article
- Molecular Identification and Antimicrobial Resistance Characteristics of Extended-Spectrum Beta-Lactamase ProducingVeterinary sciences · 2025Article
- Prevalence of ESBL-Resistant Genes in Birds in Italy-A Comprehensive Review.Animals : an open access journal from MDPI · 2025Review
- Antimicrobial Susceptibility Profiles ofAntibiotics (Basel, Switzerland) · 2025Article
- Anti-microbial resistance to β-lactams and prevalence of colicin genes among phylotypes ofVeterinary research forum : an international quarterly journal · 2025Article
- Survey on the Occurrence of Zoonotic Bacterial Pathogens in the Feces of Wolves (Microorganisms · 2024Article
- The role of New World vultures as carriers of environmental antimicrobial resistance.BMC microbiology · 2024Article
- Antimicrobial Susceptibility of Enterococci Isolated from Nestlings of Wild Birds Feeding in Supplementary Feeding Stations: The Case of the Canarian Egyptian Vulture.Pathogens (Basel, Switzerland) · 2024Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most of the studies focused on antimicrobial resistance (AMR) performed in wildlife describe Escherichia coli as the principal indicator of the selective pressure. In the present study, several species of Enterobacterales with a large panel of cephalosporin resistant (CR) genes have been isolated from wildlife in Catalonia. A total of 307 wild animals were examined to determine the prevalence of CR enterobacteria, AMR phenotypes and the presence of common carbapenem and CR genes. The overall prevalence of CR-phenotype was 13% (40/307): 17.3% in wild mammals (18/104) and 11.5% in wild birds (22/191) (p<0.01). Hedgehogs showed the highest prevalence (13.5% of 104) of the mammal specimens, and raptors the highest in bird specimen (7.3% of 191). Although CR E. coli was the most frequently isolated (45%), other CR- Enterobacterales like Klebsiella pneumoniae (20%), Citrobacter freundii (15%), Enterobacter cloacae (5%), Proteus mirabilis (5%), Providencia spp (5%) and Serratia marcescens (2.5%) were also isolated. A high diversity of CR genes was identified among the isolates, with 50% yielding blaCMY-2, 23% blaSHV-12, 20% blaCMY-1 and 18% blaCTX-M-15. Additionally, resistance to carbapenems associated to OXA-48 gene was found. Most of the CR isolates, principally K. pneumoniae and C. freundii, were multi-resistant with co-resistance to fluoroquinolones, tetracycline, sulphonamides and aminoglycosides. This study reports high prevalence of Enterobacterales harbouring a variety of CR genes and OXA-48 mediated-carbapenem resistance, all of them frequently associated to nosocomial human infections, for the first time in wild mammals and wild birds. Implementation of control measures to reduce the impact of anthropogenic pressure in the environment is urgently needed.
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