Evidence map›Paper›PMID 31381249›Full record

ArticleBJU international2020

Health-related quality of life among non-muscle-invasive bladder cancer survivors: a population-based study.

Ahrang Jung, Matthew E Nielsen, Jamie L Crandell, Mary H Palmer, Sophia K Smith, Ashley Leak Bryant, Deborah K Mayer

Open access · greenAbstract read
In one paragraph

Article in BJU international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Patient-reported outcomes in non-muscle invasive bladder cancer: a mixed-methods systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Pooled it
  3. Longitudinal data on health-related quality of life and its association with time to readmission in bladder perfusion patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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  15. Relationships among uncertainty, post-traumatic stress disorder symptoms, and quality of life in non-muscle-invasive bladder cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
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  17. Searching for a harmonious survival: the experience of quality of life of urological cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ahrang JungLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-9491-0149
Matthew E NielsenLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jamie L CrandellSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mary H PalmerSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sophia K SmithSchool of Nursing, Duke University, Durham, NC, USA.
Ashley Leak BryantLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Deborah K MayerLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USDuke University · US

Funding

INTERVENTIONS FOR PREVENTING &MANAGING CHRONIC ILLNESST32NR007091 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Cheryl L Giscombe, Cathi Barbra Propper · 1996 to 2026
$11.8M
Lineberger Comprehensive Cancer Center, University of North CarolinaNINR NIH HHS T32 NR007091Sigma Theta Tau InternationalUniversity of North Carolina at Chapel Hill
6 · The paper itself

Abstract

objectiveTo examine the effect of non-muscle-invasive bladder cancer (NMIBC) diagnosis and treatment on survivors' quality of life (QoL). PATIENTS AND

methodsOf the 5979 patients with NMIBC diagnosed between 2010 and 2014 in North Carolina, 2000 patients were randomly selected to be invited to enroll in this cross-sectional study. Data were collected by postal mail survey. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core (QLQ-C30) and the NMIBC-specific module were included in the survey to measure QoL. Descriptive statistics, t-tests, anova, and Pearson's correlation were used to describe demographics and to assess how QoL varied by sex, cancer stage, time since diagnosis, and treatment.

resultsA total of 398 survivors returned questionnaires (response rate: 23.6%). The mean QoL score for QLQ-C30 (range 0-100, higher = better QoL in all domains but symptoms) for global health status was 73.6, function domain scores ranged from 83.9 to 86.5, and scores for the top five symptoms (insomnia, fatigue, dyspnoea, pain, and financial difficulties) ranged from 14.1 to 24.3. The lowest NMIBC-specific QoL domain was sexual issues including sexual function, enjoyment, problems, and intimacy. Women had worse bowel problems, sexual function, and sexual enjoyment than men but better sexual intimacy and fewer concerns about contaminating their partner. Stage Ta had the highest global health status, followed by T1 and Tis. QoL did not vary by time since diagnosis except for sexual function. The cystectomy group (n = 21) had worse QoL in sexual function, discomfort with sexual intimacy, sexual enjoyment, and male sexual problems than the non-cystectomy group (n = 336).

conclusionSurvivors of NMIBC face a unique burden associated with their diagnosis and the often-lifelong surveillance and treatment regimens. The finding has important implications for the design of tailored supportive care interventions to improve QoL for NMIBC survivors.

Indexed as

Quality of LifeUrinary Bladder NeoplasmsAdultAgedAged, 80 and overCancer SurvivorsCross-Sectional StudiesDiagnostic Self EvaluationFemaleHumansMaleMiddle AgedNeoplasm InvasivenessNorth CarolinaProspective Studies#BladderCancerbladder cancer survivor#blcsmcystoscopynon-muscle-invasive bladder cancerquality of lifeurinary bladder neoplasms

Identifiers

PMID31381249
PMCPMC7137766
OpenAlexW2966581238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.