ArticleMicrobial biotechnology2019
Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas.
Article in Microbial biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 103 citations in OpenAlex.
- Sympatric Lepus spp. in the central Italian Alps host significantly different gut microbiotas.Scientific reports · 2026Article
- Fertility-Associated Soil Chemistry Predominantly Influence Gut Microbiota Diversity in Goitered Gazelles of the Qaidam Basin, China.Microorganisms · 2026Article
- Article
- Gut microbiome plasticity explains the altitudinal distribution pattern and adaptability in a small mammal species (Microbiology spectrum · 2026Article
- Gut bacteriome alterations during high altitude exposure: a comprehensive analysis of different species.Frontiers in microbiology · 2026Review
- Seasonal dynamics of gut microbiota in rhesus macaques (Macaca mulatta) from western Sichuan Plateau and their adaptability to high altitude climate change.Current microbiology · 2025Article
- Diet, nutrient characteristics and gut microbiome between summer and winter drive adaptive strategies of East China sika deer (Cervus nippon kopschi) in the Yangtze River basin.BMC microbiology · 2025Article
- Multi-omics reveal the gut microbiota-mediated severe foraging environment adaption of small wild ruminants in the Three-River-Source National Park, China.Integrative zoology · 2025Article
- Bacterial microbiome and their assembly processing in two sympatric desert rodents (Current zoology · 2025Article
- Synergistic Adaptations of Yak Rumen Microbiota, Metabolites and Host to Altitudinal.Microorganisms · 2025Article
- Article
- Human gut microbiota adaptation to high-altitude exposure: longitudinal analysis over acute and prolonged periods.Microbiology spectrum · 2025Article
- Investigation of the genetic diversity of gut mycobiota of the wild and laboratory mice.Microbiology spectrum · 2025Article
- Comparative study of gut microbiota reveals the adaptive strategies of gibbons living in suboptimal habitats.NPJ biofilms and microbiomes · 2025Article
- Editorial: Gut microbiota's role in high-altitude animal adaptation.Frontiers in microbiology · 2025Article
- Study on intestinal microbial communities of three different cattle populations on Qinghai-Tibet Plateau.PloS one · 2025Article
- Adaptive characteristics of the gut microbiota of the scaly-sided merganser (Frontiers in microbiology · 2025Article
- Consumption of steam explosion and fermentation-pretreated corn stover affects the growth performance of sheep by shifting the rumen microbiota community structure.Frontiers in microbiology · 2025Article
- Host habitat shapes the gut microbiomes of insular reptilian hosts in the Philippines.ISME communications · 2025Article
- Annual cycle variations in the gut microbiota of migratory black-necked cranes.Frontiers in microbiology · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite their important roles in host nutrition, metabolism and adaptability, the knowledge on how the mammalian gut microbial community assemble is relatively scanty, especially regarding the ecological mechanisms that govern microbiota along environmental gradients. To address this, we surveyed the diversity, function and ecological processes of gut microbiota in the wild plateau pika, Ochotona curzoniae, along the elevational gradient from 3106 to 4331 m on 'the Roof of the World'-Qinghai-Tibet Plateau. The results indicated that the alpha, beta and functional diversity of gut microbiota significantly increased with elevation, and elevation significantly explained the variations in the gut microbial communities, even after controlling for geographical distance, host sex and body weight. Some gene functions (e.g. nitrogen metabolism and protein kinases) associated with metabolism were enriched in the high-altitude pikas. Null model and phylogenetic analysis suggest that the relative contributions of environmental filtering responsible for local gut communities increased with elevation. In addition, deterministic processes dominated gut microbial communities in the high-altitude (more than 3694 m) pikas, while the percentages of stochastic and deterministic processes were very close in the low-altitude (3106 and 3580 m) pikas. The observed mechanisms that influence pika gut microbiota assembly and function seemed to be mainly mediated by the internal gut environment and by the external environmental pressure (i.e. lower temperature) in the harsh high-altitude environment. These findings enhance our understanding of gut microbiota assembly patterns and function in wild mammals from extreme harsh environments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.