Evidence map›Paper›PMID 31380472›Full record

ArticleJournal of spine surgery (Hong Kong)2019

Vertebral height restoration following kyphoplasty.

James H Mooney, John Amburgy, Mitchell Self, Bonita S Agee, Leah Schoel, Patrick R Pritchard, Melissa Rene Chambers

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. The challenge of OF5 vertebral fractures treatment: a modified muscle-preserving surgical technique and case-series presentation with a minimum 2-Year follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

James H MooneyDepartment of Neurological Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA.
John AmburgyDepartment of Neurological Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA.
Mitchell SelfSchool of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Bonita S AgeeDepartment of Neurological Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA.
Leah SchoelSchool of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Patrick R PritchardDepartment of Neurological Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA.
Melissa Rene ChambersDepartment of Neurological Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USNeurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKyphoplasty is a minimally invasive surgery developed to restore height and stabilize painful vertebral compression fractures (VCFs). Only small retrospective studies have addressed the correlation between the degree of vertebral height restoration as it relates to pain relief and postoperative activity levels. No definitive correlations have been established. The objective of this analysis is to determine how height restoration correlates with improvements in pain, disability and quality of life.

methodsWe assessed outcomes following kyphoplasty in 59 Medicare-eligible patients with 1-3 painful VCFs between T5 and L5 due to osteoporosis or cancer. Pre and postoperative lateral radiographs were available for fifty-nine patients and were used to measure anterior, middle and posterior vertebral body (VB) heights. The Visual Analog Scale (VAS) [range: 0 (none) to 10 (worst)] was used to prospectively measure back pain pre and post-operatively in all patients. Pre and post-operative measurements of disability and quality of life were retrospectively collected using the Roland Morris Disability Index (RMDI) [range: 0 (no disability) to 24 (high disability)] and EuroQol5-Domain scale (EQ5D) [range: -0.11 (poor quality of life) to 1.0 (perfect health)]. Pearson correlations and linear regression models were analyzed for association of VB height improvement with outcomes.

resultsNeither Pearson correlations (r coefficient range: 0.001-0.152) nor linear regression models (R

conclusionsThis is one of the largest studies to date assessing associations of VB height restoration following kyphoplasty with prospective measurements of pain and retrospective evaluation of disability and quality of life using validated instruments. Although a majority of patients in this cohort demonstrated increased vertebral heights and significant improvements in outcomes, none of the outcomes showed association with height improvements. Regardless of vertebral height improvements, most patients had improved pain, function and quality of life.

Indexed as

cancerkyphoplastyosteoporosispatient outcomesvertebral augmentationvertebral body height restoration (VB height restoration)Vertebral compression fracture (VCF)

Identifiers

PMID31380472
PMCPMC6626734
OpenAlexW2936281821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.