ReviewFrontiers in bioengineering and biotechnology2019
Titanium-Tissue Interface Reaction and Its Control With Surface Treatment.
Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed, 2 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- Effectiveness of strontium/silver-based titanium surface coatings in improving antibacterial and osteogenic implant characteristics: a systematic review ofFrontiers in bioengineering and biotechnology · 2024Pooled it
- Toxicity Evaluation of TiOFrontiers in bioengineering and biotechnology · 2020Pooled it
- Confirmation of Safety of Titanium Wire in Sternotomy Closure, A Randomized Prospective Study.The Thoracic and cardiovascular surgeon · 2024Trial
- Electronic structure and multiscale modelling of the hydroxyapatite-TiORSC advances · 2026Review
- Acid-Induced Surface Degradation of Metallic Biomaterials: Alloy-Dependent Behavior and Implications for Surface Functionality.Journal of functional biomaterials · 2026Article
- A Redox Amplification Interface Linking Mitochondrial Dysfunction, Immune-Derived Oxidants, and Biomaterial Electrochemistry in Chronic Inflammation.International journal of molecular sciences · 2026Review
- Use of locking humeral stems in reverse total shoulder arthroplasty for complex proximal humerus fractures: a scoping review.JSES reviews, reports, and techniques · 2026Review
- Surface Modification of Titanium Using Nano-Hydroxyapatite: A Comparative Microhardness Study.Cureus · 2026Article
- Effect of Rare-Earth Element Microdoping on Ti-6Al-7Nb Alloys for Biomedical Applications: Materials Characterization and In Vivo Biocompatibility Tests.Materials (Basel, Switzerland) · 2026Article
- Grain Size and Electrochemical Surface Modification Effects on Corrosion, Biological, and Technological Properties of CP Titanium Implants.Journal of functional biomaterials · 2025Article
- Bone Formation and Anti-Inflammatory Properties of Iodine-Loaded Titanium Implants: An Animal Study.Materials (Basel, Switzerland) · 2025Article
- Novel synthesis of AlJournal of materials science. Materials in medicine · 2025Article
- A comparative study of a novel absorbable cranial flap fixation system and Aesculap CranioFix.Chinese neurosurgical journal · 2025Article
- Laser-Driven Surface Alloying of Ti6Al4V: Coupled Microstructural Evolution, Phase Behavior, and Mechanical Performance.Materials (Basel, Switzerland) · 2025Article
- Electrochemical Catheter Hub Operated by a Wearable Micropotentiostat Prevents Acinetobacter baumannii Infection In Vitro.Biotechnology and bioengineering · 2025Article
- Hydroxyapatite-Complexed Type I Collagen and Fibrinogen-Modified Porous Titanium Alloy Scaffold: Promoting Osteogenesis and Soft Tissue Integration.Micromachines · 2025Article
- Macrophage-associated biocompatibility of titanium revealed by analyzing foreign body reaction at bone-implant interface.The journal of advanced prosthodontics · 2025Article
- Article
- Laser Mechanized Physicochemical Characterizations on the Surface of Implants and Dental Abutments.Cureus · 2025Article
- A biosynthetic thumb prosthesis.npj biomedical innovations · 2025Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium (Ti) and its alloys are widely used for medical and dental implant devices-artificial joints, bone fixators, spinal fixators, dental implant, etc. -because they show excellent corrosion resistance and good hard-tissue compatibility (bone formation and bone bonding ability). Osseointegration is the first requirement of the interface structure between titanium and bone tissue. This concept of osseointegration was immediately spread to dental-materials researchers worldwide to show the advantages of titanium as an implant material compared with other metals. Since the concept of osseointegration was developed, the cause of osseointegration has been actively investigated. The surface chemical state, adsorption characteristics of protein, and bone tissue formation process have also been evaluated. To accelerate osseointegration, roughened and porous surfaces are effective. HA and TiO
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.