Evidence map›Paper›PMID 31380321›Full record

Trial reportCanadian journal of gastroenterology & hepatology2019

Telbivudine Treatment during Late Pregnancy Prevents Mother-to-Child Transmission of Hepatitis B Virus: A Retrospective Study.

Mengzhi Cai, Yanli Hao, Jianxin Zhong, Wei Yao, Xia Cao, Guifang Gu, Gang Qin

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Canadian journal of gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mengzhi CaiCenter for Liver Diseases, Nantong Third People's Hospital, Nantong University, Nantong 226006, China.ORCID 0000-0002-5195-407X
Yanli HaoCenter for Liver Diseases, Nantong Third People's Hospital, Nantong University, Nantong 226006, China.ORCID 0000-0002-2692-5496
Jianxin ZhongDepartment of Obstetrics and Gynaecology, Affiliated Hospital of Nantong University, Nantong 226001, China.ORCID 0000-0002-6736-7558
Wei YaoDepartment of Obstetrics and Gynaecology, Affiliated Hospital of Nantong University, Nantong 226001, China.ORCID 0000-0002-6298-5859
Xia CaoDepartment of Obstetrics and Gynaecology, Nantong Third People's Hospital, Nantong University, Nantong 226006, China.ORCID 0000-0002-2457-0986
Guifang GuDepartment of Obstetrics and Gynaecology, Nantong Third People's Hospital, Nantong University, Nantong 226006, China.ORCID 0000-0002-8615-0936
Gang QinCenter for Liver Diseases, Nantong Third People's Hospital, Nantong University, Nantong 226006, China.ORCID 0000-0002-4363-2572
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the efficacy of telbivudine (LdT) in blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) during late pregnancy. Methods: A total of 651 pregnant women aged 18-40 in Nantong Third People's Hospital and Hospital affiliated to Nantong University with positive hepatitis B surface antigen (HBsAg) and HBV DNA were enrolled between January 2011 and December 2015. Patients with HBV DNA≥10 Results: At 7 months and 1 year postpartum, the basal HBV DNA serum level of treated patients declined significantly ( Conclusion: For pregnant women with HBV DNA≥10

Indexed as

Hepatitis B virusPrenatal CareAdolescentAdultAntiviral AgentsFemaleHepatitis BHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPregnancy Trimester, ThirdRetrospective StudiesTelbivudineTreatment OutcomeAntiviral AgentsTelbivudine

Identifiers

PMID31380321
PMCPMC6652084
OpenAlexW2959417576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.