Evidence map›Paper›PMID 31380274›Full record

ArticleFrontiers in oncology2019

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis.

Hanyuan Shen, Zhipeng Qu, Yuka Harata-Lee, Thazin Nwe Aung, Jian Cui, Wei Wang, R Daniel Kortschak, David L Adelson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Effect ofFrontiers in pharmacology · 2025
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  13. Molecular medicine reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hanyuan ShenZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Zhipeng QuZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Yuka Harata-LeeZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Thazin Nwe AungZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Jian CuiZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
Wei WangZhendong Research Institute, Shanxi-Zhendong Pharmaceutical Co., Ltd, Beijing, China.
R Daniel KortschakZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
David L AdelsonZhendong Australia-China Centre for Molecular Chinese Medicine, School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
University of Adelaide · AUShanxi Zhendong Pharmaceutical (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal compatibility is the knowledge of which herbs to combine in traditional Chinese medicine (TCM) formulations. The lack of understanding of herbal compatibility is one of the key problems for the application and popularization of TCM in western society. Because of the chemical complexity of herbal medicines, it is simpler to begin to conduct compatibility research based on herbs rather than component plant secondary metabolites. We have used transcriptome analysis to explore the effects and interactions of two plant extracts (Kushen and Baituling) combined in Compound Kushen Injection (CKI). Based on shared chemical compounds and

Indexed as

cancer treatmentCompound Kushen Injectionherb combinationtraditional Chinese medicinetranscriptome

Identifiers

PMID31380274
PMCPMC6660286
OpenAlexW2961591376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.