Evidence map›Paper›PMID 31380183›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019

Radiopharmaceuticals and Fluorescein Sodium Mediated Triple-Modality Molecular Imaging Allows Precise Image-Guided Tumor Surgery.

Sheng Zheng, Zeyu Zhang, Yawei Qu, Xiaojun Zhang, Hongbo Guo, Xiaojing Shi, Meishan Cai, Caiguang Cao, Zhenhua Hu, Haifeng Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Intraoperative fluorescence molecular imaging accelerates the coming of precision surgery in China.European journal of nuclear medicine and molecular imaging · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Radiopharmaceutical and EuJournal of nanobiotechnology · 2021
    Article
  19. Foods (Basel, Switzerland) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sheng ZhengDepartment of Gastroenterology The Third Medical Centre Chinese PLA General Hospital Beijing 100039 China.
Zeyu ZhangSchool of Life Science and Technology Xidian University Xi'an 710071 China.
Yawei QuDepartment of Gastroenterology The Third Medical Centre Chinese PLA General Hospital Beijing 100039 China.
Xiaojun ZhangDepartment of Nuclear Medicine Chinese PLA General Hospital Beijing 100853 China.
Hongbo GuoSchool of Information Sciences and Technology Northwest University Xi'an 710127 China.
Xiaojing ShiCAS Key Laboratory of Molecular Imaging Beijing Key Laboratory of Molecular Imaging The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100190 China.
Meishan CaiCAS Key Laboratory of Molecular Imaging Beijing Key Laboratory of Molecular Imaging The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100190 China.
Caiguang CaoCAS Key Laboratory of Molecular Imaging Beijing Key Laboratory of Molecular Imaging The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100190 China.
Zhenhua HuCAS Key Laboratory of Molecular Imaging Beijing Key Laboratory of Molecular Imaging The State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100190 China.
Haifeng LiuDepartment of Gastroenterology The Third Medical Centre Chinese PLA General Hospital Beijing 100039 China.
Jie TianSchool of Life Science and Technology Xidian University Xi'an 710071 China.ORCID https://orcid.org/0000-0002-9523-2271
Chinese PLA General Hospital · CNShandong Institute of Automation · CNXidian University · CNNorthwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical resection is the most effective method for malignant tumor treatments. However, conventional imaging cannot fully satisfy the clinical needs of surgical navigation. This study presents a novel triple-modality positron emission tomography (PET)-Cerenkov radiation energy transfer (CRET)-confocal laser endomicroscopy (CLE) imaging strategy for intraoperative tumor imaging and surgical navigation. Using clinical radiopharmaceuticals and fluorescein sodium (FS), this strategy can accurately detect the tumor and guide the tumor surgery. The FS emission property under Cerenkov radiation excitation is investigated using 2-deoxy-2-

Indexed as

Cerenkov luminescence imagingCerenkov radiation energy transferconfocal laser endomicroscopymalignant tumorspositron emission computed tomography

Identifiers

PMID31380183
PMCPMC6662088
OpenAlexW2941731342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.