Evidence map›Paper›PMID 31380066›Full record

ArticleEcology and evolution2019

Heterozygosity at neutral and immune loci is not associated with neonatal mortality due to microbial infection in Antarctic fur seals.

Vivienne Litzke, Meinolf Ottensmann, Jaume Forcada, Louise Heitzmann, Joseph Ivan Hoffman

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Vivienne LitzkeDepartment of Animal Behaviour Bielefeld University Bielefeld Germany.ORCID https://orcid.org/0000-0002-3170-6060
Meinolf OttensmannDepartment of Animal Behaviour Bielefeld University Bielefeld Germany.
Jaume ForcadaBritish Antarctic Survey, High Cross Cambridge UK.
Louise HeitzmannInstitut des Sciences de l'Evolution CNRS Montpellier France.
Joseph Ivan HoffmanDepartment of Animal Behaviour Bielefeld University Bielefeld Germany.ORCID https://orcid.org/0000-0001-5895-8949
Bielefeld University · DEBritish Antarctic Survey · GBCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have reported correlations between the heterozygosity of genetic markers and fitness. These heterozygosity-fitness correlations (HFCs) play a central role in evolutionary and conservation biology, yet their mechanistic basis remains open to debate. For example, fitness associations have been widely reported at both neutral and functional loci, yet few studies have directly compared the two, making it difficult to gauge the relative contributions of genome-wide inbreeding and specific functional genes to fitness. Here, we compared the effects of neutral and immune gene heterozygosity on death from bacterial infection in Antarctic fur seal (

Indexed as

Antarctic fur seal (Arctocephalus gazella)bacterial infectionheterozygosity–fitness correlation (HFC)inbreedingpinniped

Identifiers

PMID31380066
PMCPMC6662382
OpenAlexW2950462180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.