Evidence map›Paper›PMID 31380018›Full record

ArticleEcology and evolution2019

Signals of positive selection in mitochondrial protein-coding genes of woolly mammoth: Adaptation to extreme environments?

Jacob Njaramba Ngatia, Tian Ming Lan, Thi Dao Dinh, Le Zhang, Ahmed Khalid Ahmed, Yan Chun Xu

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jacob Njaramba NgatiaCollege of Wildlife Resources Northeast Forestry University Harbin China.
Tian Ming LanBGI-Shenzhen Shenzhen China.
Thi Dao DinhCollege of Wildlife Resources Northeast Forestry University Harbin China.
Le ZhangCollege of Wildlife Resources Northeast Forestry University Harbin China.
Ahmed Khalid AhmedCollege of Wildlife Resources Northeast Forestry University Harbin China.ORCID https://orcid.org/0000-0001-8301-8510
Yan Chun XuCollege of Wildlife Resources Northeast Forestry University Harbin China.ORCID https://orcid.org/0000-0003-0397-4292
Northeast Forestry University · CNBGI Group (China) · CNState Forestry and Grassland Administration · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammoths originated in warm and equatorial Africa and later colonized cold and high-latitude environments. Studies on nuclear genes suggest that woolly mammoth had evolved genetic variations involved in processes relevant to cold tolerance, including lipid metabolism and thermogenesis, and adaptation to extremely varied light and darkness cycles. The mitochondria is a major regulator of cellular energy metabolism, thus the mitogenome of mammoths may also exhibit adaptive evolution. However, little is yet known in this regard. In this study, we analyzed mitochondrial protein-coding genes (MPCGs) sequences of 75 broadly distributed woolly mammoths (

Indexed as

Mammuthus primigeniusmitochondrial genomemitolineagespositive selectionwoolly mammoth

Identifiers

PMID31380018
PMCPMC6662336
OpenAlexW2944171186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.