Evidence map›Paper›PMID 31379989›Full record

ArticleOxidative medicine and cellular longevity2019

The Ameliorative Effects of the Ethyl Acetate Extract of

Joonsoo Kim, Govindarajan Karthivashan, Mee-Hyang Kweon, Deuk-Hoi Kim, Dong-Kug Choi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. ValorizingInternational journal of food science · 2026
    Article
  3. Anti-Obesity and Anti-Dyslipidemic Effects ofFoods (Basel, Switzerland) · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Antioxidants (Basel, Switzerland) · 2021
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joonsoo KimDepartment of Applied Life Sciences, Graduate school of Konkuk University, Research Institute of Inflammatory Diseases, Chungju 27478, Republic of Korea.
Govindarajan KarthivashanDepartment of Applied Life Sciences, Graduate school of Konkuk University, Research Institute of Inflammatory Diseases, Chungju 27478, Republic of Korea.ORCID https://orcid.org/0000-0002-6257-2632
Mee-Hyang KweonResearch Center, Phyto Corporation, Seoul 08826, Republic of Korea.
Deuk-Hoi KimResearch Center, Phyto Corporation, Seoul 08826, Republic of Korea.
Dong-Kug ChoiDepartment of Applied Life Sciences, Graduate school of Konkuk University, Research Institute of Inflammatory Diseases, Chungju 27478, Republic of Korea.ORCID https://orcid.org/0000-0001-7041-1524
Konkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperactivation of microglia, the resident innate immune cells of the central nervous system, exacerbates various neurodegenerative disorders, including Parkinson's disease (PD). Parkinson's disease is generally characterized by a severe loss of dopaminergic neurons in the nigrostriatal pathway, with substantial neuroinflammation and motor deficits. This was experimentally replicated in animal models, using neurotoxins, i.e., LPS (lipopolysaccharides) and MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

Indexed as

AcetatesAnimalsAntioxidantsChenopodiaceaeCyclooxygenase 2Disease Models, AnimalIsoflavonesLipopolysaccharidesMaleMiceMice, Inbred C57BLMicrogliaMPTP PoisoningNeuroprotective AgentsNitric Oxide Synthase Type IIPlant ExtractsAcetatesAntioxidantsCyclooxygenase 2ethyl acetateirilin BIsoflavonesLipopolysaccharidesNeuroprotective AgentsNitric Oxide Synthase Type IIPlant ExtractsReactive Oxygen Species

Identifiers

PMID31379989
PMCPMC6652089
OpenAlexW2959190643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.