Evidence map›Paper›PMID 31379915›Full record

ArticleFrontiers in genetics2019

Human-Derived Corneal Epithelial Cells Expressing Cell Cycle Regulators as a New Resource for

Tomokazu Fukuda, Ryo Gouko, Takahiro Eitsuka, Ryusei Suzuki, Kohei Takahashi, Kiyotaka Nakagawa, Eriko Sugano, Hiroshi Tomita, Tohru Kiyono

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Tea tree oil action on human corneal epithelial cells biological activity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tomokazu FukudaGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Ryo GoukoGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Takahiro EitsukaGraduate School of Agricultural Science, Tohoku University, Aoba-ku, Sendai, Japan.
Ryusei SuzukiGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Kohei TakahashiGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Kiyotaka NakagawaGraduate School of Agricultural Science, Tohoku University, Aoba-ku, Sendai, Japan.
Eriko SuganoGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Hiroshi TomitaGraduate School of Science and Engineering, Iwate University, Morioka, Japan.
Tohru KiyonoDivision of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, Tokyo, Japan.
Iwate University · JPTohoku University · JPGenesis Research Institute · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Draize test has been used on rabbits since the 1960s to evaluate the irritation caused by commercial chemicals in products such as cosmetics or hairdressing products. However, since 2003, such tests, including the Draize test for cosmetics, have been prohibited in European countries because they are considered problematic to animal welfare. For this reason, replacement of

Indexed as

cell cycle regulatorscorneal epithelial cellscyclin D1cyclin-dependent kinase 4immortalizationtelomerase reverse transcriptase

Identifiers

PMID31379915
PMCPMC6646426
OpenAlexW2956869982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.