Evidence map›Paper›PMID 31379866›Full record

ReviewFrontiers in immunology2019

Protective Antibodies Against Influenza Proteins.

Herbey O Padilla-Quirarte, Delia V Lopez-Guerrero, Lourdes Gutierrez-Xicotencatl, Fernando Esquivel-Guadarrama

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 97 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Herbey O Padilla-QuirarteLIV, Facultad de Medicina, Universidad Autonoma del Estado de Morelos, Cuernavaca, Mexico.
Delia V Lopez-GuerreroFacultad de Nutricion, Universidad Autonoma del Estado de Morelos, Cuernavaca, Mexico.
Lourdes Gutierrez-XicotencatlCentro de Investigaciones Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Publica, Cuernavaca, Mexico.
Fernando Esquivel-GuadarramaLIV, Facultad de Medicina, Universidad Autonoma del Estado de Morelos, Cuernavaca, Mexico.
Universidad Autónoma del Estado de Morelos · MXInstituto Nacional de Salud Pública · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influenza A virus infection continues to be a threat to the human population. The seasonal variation of the virus and the likelihood of periodical pandemics caused by completely new virus strains make it difficult to produce vaccines that efficiently protect against this infection. Antibodies (Abs) are very important in preventing the infection and in blocking virus propagation once the infection has taken place. However, the precise protection mechanism provided by these Abs still needs to be established. Furthermore, most research has focused on Abs directed to the globular head domain of hemagglutinin (HA). However, other domains of HA (like the stem) and other proteins are also able to elicit protective Ab responses. In this article, we review the current knowledge about the role of both neutralizing and non-neutralizing anti-influenza proteins Abs that play a protective role during infection or vaccination.

Indexed as

Antibodies, ViralAntigens, ViralEpitopes, B-LymphocyteHumansInfluenza A virusInfluenza, HumanInfluenza VaccinesAntibodies, ViralAntigens, ViralEpitopes, B-LymphocyteInfluenza Vaccinesinfluenza A virusinfluenza proteinsneutralizing antibodiesnon-neutralizing antibidiesprotective antibodies

Identifiers

PMID31379866
PMCPMC6657620
OpenAlexW2955239921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.