Evidence map›Paper›PMID 31379844›Full record

ArticleFrontiers in immunology2019

Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han.

Zhihui Deng, Jun Zhao, Siqi Cai, Ying Qi, Qiong Yu, Maureen P Martin, Xiaojiang Gao, Rui Chen, Jiacai Zhuo, Jianxin Zhen and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Frontiers in genetics · 2025
    Article
  6. Article
  7. Frequency of HLA alleles and KIR Ligands in Acute Myeloid Leukemia in Indian Cohort.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

Zhihui DengImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Jun ZhaoSchool of Ophthalmology and Optometry, Shenzhen Eye Hospital, Shenzhen University, Shenzhen, China.
Siqi CaiImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Ying QiBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Qiong YuImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Maureen P MartinBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Xiaojiang GaoBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Rui ChenImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Jiacai ZhuoDepartment of Hematology, Shenzhen Second People's Hospital, Shenzhen, China.
Jianxin ZhenImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Mingjie ZhangResearch and Development Department, Shenzhen Hank Bioengineering Institute, Shenzhen, China.
Guobin ZhangImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Liumei HeImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Hongyan ZouImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Liang LuImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Weigang ZhuImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Wenxu HongImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Mary CarringtonBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Paul J NormanDivision of Biomedical Informatics and Personalized Medicine, Department of Microbiology and Immunology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Shenzhen Blood Center · CNFrederick National Laboratory for Cancer Research · USShenzhen Hanke Bioengineering (China) · CNShenzhen Second People's Hospital · CNShenzhen University · CNUniversity of Colorado Anschutz Medical Campus · US

Funding

Insights Into Immune-Related Diseases Born from Population GenomicsU01AI090905 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Paul John Norman · 2010 to 2026
$10.9M
KIR association studies in neurological diseasesU19NS095774 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERNANDEZ-VINA, MARCELO, OKSENBERG, JORGE R. · 2015 to 2019
$7.0M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENIAID NIH HHS U01 AI090905NINDS NIH HHS U19 NS095774
6 · The paper itself

Abstract

Interactions of human natural killer (NK) cell inhibitory receptors with polymorphic HLA-A, -B and -C molecules educate NK cells for immune surveillance against tumor cells. The

Indexed as

AdultAsian PeopleChildFemaleGenotypeHistocompatibility Antigens Class IHumansKiller Cells, NaturalLeukemiaMaleReceptors, KIRHistocompatibility Antigens Class IReceptors, KIRALLAMLChinese Southern HanCMLHLAKIRleukemiaNHL

Identifiers

PMID31379844
PMCPMC6646668
OpenAlexW2956968598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.