Evidence map›Paper›PMID 31379826›Full record

ArticleFrontiers in immunology2019

NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity.

Marina Sokolova, Ivar Sjaastad, Mieke C Louwe, Katrine Alfsnes, Jan Magnus Aronsen, Lili Zhang, Solveig B Haugstad, Bård Andre Bendiksen, Jonas Øgaard, Marte Bliksøen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  4. Article
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  8. Review
  9. Role of epicardial adipose tissue in heart failure with preserved ejection fraction: An emerging molecular mechanism and therapeutic potential.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
  10. Obesity accelerates cardiovascular ageing.European heart journal · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. NOD-like Receptors-Emerging Links to Obesity and Associated Morbidities.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Sodium-Glucose Cotransporter 2 Inhibitors and Cardiac Remodeling.Journal of cardiovascular translational research · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Marina SokolovaResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Ivar SjaastadK.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Mieke C LouweResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Katrine AlfsnesResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Jan Magnus AronsenInstitute for Experimental Medical Research, Oslo University Hospital Ullevål, Oslo, Norway.
Lili ZhangCenter for Heart Failure Research, University of Oslo, Oslo, Norway.
Solveig B HaugstadCenter for Heart Failure Research, University of Oslo, Oslo, Norway.
Bård Andre BendiksenCenter for Heart Failure Research, University of Oslo, Oslo, Norway.
Jonas ØgaardResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Marte BliksøenResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Egil LienDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA, United States.
Rolf K BergeDepartment of Clinical Science, Department of Heart Disease, Haukeland University Hospital, University of Bergen, Bergen, Norway.
Pål AukrustResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Trine RanheimResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Arne YndestadResearch Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NOInstitutt for Eksperimentell Medisinsk Forskning · NONorwegian University of Science and Technology · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDiet, High-FatInflammasomesInflammationInsulinInsulin ResistanceLiverMaleMiceMice, Inbred C57BLMice, KnockoutMyocardiumNLR Family, Pyrin Domain-Containing 3 ProteinObesitySignal TransductionInflammasomesInsulinNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousecardiac remodelinghearthigh-fat dietinflammasomeNLRP3obesity

Identifiers

PMID31379826
PMCPMC6648799
OpenAlexW2962621157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.