Evidence map›Paper›PMID 31379789›Full record

ArticleFrontiers in microbiology2019

Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile

Héctor Osorio, Erin Mettert, Patricia Kiley, Mark Dopson, Eugenia Jedlicki, David S Holmes

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Héctor OsorioCenter for Bioinformatics and Genome Biology, Fundación Ciencia y Vida, Santiago, Chile.
Erin MettertDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, United States.
Patricia KileyDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, United States.
Mark DopsonCentre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, Kalmar, Sweden.
Eugenia JedlickiCenter for Bioinformatics and Genome Biology, Fundación Ciencia y Vida, Santiago, Chile.
David S HolmesCenter for Bioinformatics and Genome Biology, Fundación Ciencia y Vida, Santiago, Chile.
Fundación Ciencia and Vida · CLUniversity of Wisconsin–Madison · USLinnaeus University · SEUniversidad Mayor · CL

Funding

The Regulation of Gene Expression by OxygenR01GM045844 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KILEY, PATRICIA J · 1991 to 2012
$4.4M
Bacterial anaerobic iron homeostasisR01GM115894 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KILEY, PATRICIA J · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM045844NIGMS NIH HHS R01 GM115894
6 · The paper itself

Abstract

The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled by the fumarate nitrate reduction transcription factor (FNR) that senses oxygen via an oxygen-sensitive [4Fe-4S]

Indexed as

anaerobic regulationbiominingDNA bindingfumarate nitrate reductaseiron-sulfur clustermicrobial ecologytranscriptional regulation

Identifiers

PMID31379789
PMCPMC6659574
OpenAlexW2956652622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.