Evidence map›Paper›PMID 31379748›Full record

ReviewFrontiers in endocrinology2019

Hypertension in Thyroid Disorders.

Eszter Berta, Inez Lengyel, Sándor Halmi, Miklós Zrínyi, Annamária Erdei, Mariann Harangi, Dénes Páll, Endre V Nagy, Miklós Bodor

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Cardiovascular Findings and Effects of Caffeine on Experimental Hypothyroidism.Endocrine, metabolic & immune disorders drug targets · 2025
    Article
  18. Review
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Eszter BertaDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Inez LengyelDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Sándor HalmiDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Miklós ZrínyiCoordination Center for Drug Development, University of Debrecen, Debrecen, Hungary.
Annamária ErdeiDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Mariann HarangiDepartment of Metabolism, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Dénes PállCoordination Center for Drug Development, University of Debrecen, Debrecen, Hungary.
Endre V NagyDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Miklós BodorDepartment of Endocrinology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial hypertension represents a major global health concern; more than one fourth of the population is affected by high blood pressure. Albeit the underlying cause of the disease remains unclear in the vast majority of the cases, ~10% are of secondary origin. Endocrine disorders are common illnesses and some of them may lead to elevated blood pressure, among which thyroid diseases are of high prevalence and often overlooked, especially in mild cases. Overt and subclinical hyper- and hypothyroidism can both lead to (mostly mild) hypertension; however, the underlying mechanisms are only partially understood. The results of clinical studies are often controversial. During the past decades, some genetic mutations in the hypothalamus-pituitary-thyroid axis with cardiovascular consequences were revealed. Atherosclerotic changes resulting from lipid abnormalities due to thyroid dysfunction also affect the vasculature and can cause elevated blood pressure. The review gives a synopsis of our knowledge how thyroid hormone metabolism and functional thyroid diseases affect the cardiovascular system, their negative impact and causative role in the development of hypertension.

Indexed as

arterial stiffnessblood pressurecardiovascular riskendocrinehypertensionhyperthyroidismhypothyroidismthyroid

Identifiers

PMID31379748
PMCPMC6652798
OpenAlexW2959086694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.