Evidence map›Paper›PMID 31379738›Full record

ArticleFrontiers in endocrinology2019

Androgens Profile in Blood Serum and Follicular Fluid of Women With Poor Ovarian Response During Controlled Ovarian Stimulation Reveals Differences Amongst POSEIDON Stratification Groups: A Pilot Study.

Ariel Fuentes, Karina Sequeira, Alejandro Tapia-Pizarro, Alex Muñoz, Abril Salinas, Pablo Céspedes, Javier Escalona, Ana Godoy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ariel FuentesFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Karina SequeiraFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Alejandro Tapia-PizarroFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Alex MuñozFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Abril SalinasFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Pablo CéspedesFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Javier EscalonaFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Ana GodoyFaculty of Medicine, Hospital San Borja-Arriarán, Institute of Maternal and Child Research (IDIMI), Universidad de Chile, Santiago, Chile.
Hospital San Borja Arriarán · CLUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with poor ovarian response (POR) to exogenous gonadotropins stimulation for assisted reproductive technology (ART) have decreased circulating androgens during spontaneous cycles. The Patient-Oriented Strategies Encompassing Individualized Oocyte Number (POSEIDON) is a 4-tier stratification of women with POR to controlled ovarian stimulation (COH) based on age and biomarkers of ovarian reserve has been proposed to maximize the clinical management of this group for ART. The aim of the present study was to characterize the levels of androgens during COH in follicular fluid (FF) and serum in POSEIDON subgroups and compared them with women of normal ovarian response. Sixty nine consecutive patients undergoing ART were included and testosterone, androstenedione, dehydroepiandrosterone sulfate (DHEA-S), estradiol, sex hormone-binding globulin (SHBG), and insulin-like growth factor 1 (IGF-1) were measured in serum and FF collected at the time of oocyte pick-up. The number of retrieved oocytes was registered for each patient for their allocation to the respective POSEIDON subgroup. The control group comprised 19 women and the POSEIDON group 1 (age < 35, normal ovarian reserve biomarkers)

Indexed as

androgensDHEA-Sfollicular fluidpoor ovarian responsePOSEIDON

Identifiers

PMID31379738
PMCPMC6646462
OpenAlexW2957226194

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.