ReviewFrontiers in neurology2019
Network Perspectives on Epilepsy Using EEG/MEG Source Connectivity.
Review in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Electroencephalography, Magnetoencephalography, and Cognitive Reserve: A Systematic Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021Pooled it
- EEG CONNECT: A proposed reporting checklist for EEG-based connectivity studies in clinical epilepsy research.Epilepsia open · 2026Review
- PSD-LW-DCN: a generalizable power spectral density based lightweight deep convolutional neural network for seizure detection.Scientific reports · 2026Article
- On the virtues and limitations of Granger-causal brain connectivity estimate: Critical analysis using neural mass models.Network neuroscience (Cambridge, Mass.) · 2026Article
- Biomarkers for Epilepsy Deep Brain Stimulation.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2025Review
- Population-based spectral characteristics of normal interictal scalp EEG inform diagnosis and treatment planning in focal epilepsy.Scientific reports · 2025Article
- Frequency-band specific directed connectivity networks reveal functional disruptions and pathogenic patterns in temporal lobe epilepsy: a MEG study.Scientific reports · 2025Article
- Network Analysis of Depression Using Magnetoencephalogram Based on Polynomial Kernel Granger Causality.Entropy (Basel, Switzerland) · 2023Article
- The time-evolving epileptic brain network: concepts, definitions, accomplishments, perspectives.Frontiers in network physiology · 2023Review
- EEG biomarker candidates for the identification of epilepsy.Clinical neurophysiology practice · 2023Review
- Interictal Functional Connectivity in Focal Refractory Epilepsies Investigated by Intracranial EEG.Brain connectivity · 2022Review
- High Dimensional Convolutional Neural Network for EEG Connectivity-Based Diagnosis of ADHD.Journal of biomedical physics & engineering · 2022Article
- Is Functional Connectivity after a First Unprovoked Seizure Different Based on Subsequent Seizures and Future Diagnosis of Epilepsy?Journal of epilepsy research · 2022Article
- Modeling Brain Functional Connectivity Patterns during an Isometric Arm Force Exertion Task at Different Levels of Perceived Exertion: A Graph Theoretical Approach.Brain sciences · 2022Article
- Network analysis of preictal iEEG reveals changes in network structure preceding seizure onset.Scientific reports · 2022Article
- Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model.Brain : a journal of neurology · 2022Article
- Virtual intracranial EEG signals reconstructed from MEG with potential for epilepsy surgery.Nature communications · 2022Article
- Alterations in the default mode network in rolandic epilepsy with mild spike-wave index in non-rapid eye movement sleep.Frontiers in neuroscience · 2022Article
- Networks of cortical activity in infants with epilepsy.Brain communications · 2022Article
- Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy.Nature reviews. Neurology · 2021Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolution of EEG/MEG source connectivity is both, a promising, and controversial advance in the characterization of epileptic brain activity. In this narrative review we elucidate the potential of this technology to provide an intuitive view of the epileptic network at its origin, the different brain regions involved in the epilepsy, without the limitation of electrodes at the scalp level. Several studies have confirmed the added value of using source connectivity to localize the seizure onset zone and irritative zone or to quantify the propagation of epileptic activity over time. It has been shown in pilot studies that source connectivity has the potential to obtain prognostic correlates, to assist in the diagnosis of the epilepsy type even in the absence of visually noticeable epileptic activity in the EEG/MEG, and to predict treatment outcome. Nevertheless, prospective validation studies in large and heterogeneous patient cohorts are still lacking and are needed to bring these techniques into clinical use. Moreover, the methodological approach is challenging, with several poorly examined parameters that most likely impact the resulting network patterns. These fundamental challenges affect all potential applications of EEG/MEG source connectivity analysis, be it in a resting, spiking, or ictal state, and also its application to cognitive activation of the eloquent area in presurgical evaluation. However, such method can allow unique insights into physiological and pathological brain functions and have great potential in (clinical) neuroscience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.