ArticleFrontiers in human neuroscience2019
The Different Brain Mechanisms of Object and Spatial Working Memory: Voxel-Based Morphometry and Resting-State Functional Connectivity.
Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
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- MCI-LB brain networks reorganization in relation to specific cognitive domains deficits.Scientific reports · 2026Article
- Prefrontal contributions to the executive control of visuospatial working memory across primate species.Frontiers in neuroanatomy · 2026Review
- Hippocampal relational memory and spatial reconstruction: where are we at and where are we bound?Frontiers in cognition · 2026Review
- Memory in Psychiatric Disorders: A Review.Life (Basel, Switzerland) · 2025Review
- Sex and age differences on how testosterone relates to brain activity during working memory among adolescents and young adults.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The Left Insula Bridges Cognition, Emotion, and Brain Structure: A Multilayer Network Analysis of the Human Connectome Project-Young Adult.bioRxiv : the preprint server for biology · 2025Article
- Anterior prefrontal EEG theta activities indicate memory and executive functions in patients with epilepsy.Epilepsia · 2025Article
- Distinct Functional Connectivity Patterns of Brain Networks Involved in Motor Planning Underlie Verbal and Spatial Working Memory.Brain and behavior · 2025Article
- Brain activity in different brain areas of patients with diabetic vitreous hemorrhage according to voxel-based morphometry.International journal of ophthalmology · 2025Article
- Intrinsic functional networks for distinct sources of error in visual working memory.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Task-specific topology of brain networks supporting working memory and inhibition.Human brain mapping · 2024Article
- Enhancing Working Memory and Reducing Anxiety in University Students: A Neurofeedback Approach.Brain sciences · 2024Article
- Differential spatial working memory-related functional network reconfiguration in young and older adults.Network neuroscience (Cambridge, Mass.) · 2024Article
- Cognitive neuroscience perspective on memory: overview and summary.Frontiers in human neuroscience · 2023Article
- Increased brain iron in patients with thyroid-associated ophthalmopathy: a whole-brain analysis.Frontiers in endocrinology · 2023Article
- Brain microstructural alterations in the left precuneus mediate the association between KIBRA polymorphism and working memory in healthy adults: a diffusion kurtosis imaging study.Brain imaging and behavior · 2022Article
- Effects of different virtual reality technology driven dual-tasking paradigms on posture and saccadic eye movements in healthy older adults.Scientific reports · 2022Article
- Intrinsic network changes associated with cognitive impairment in patients with hearing loss and tinnitus: a resting-state functional magnetic resonance imaging study.Annals of translational medicine · 2022Article
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6 authors.
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Abstract
In working memory (WM), the ability to concurrently integrate different types of information and to maintain or manipulate them promotes the flow of ongoing tasks. WM is a key component of normal human cognition. In this study, we applied a combined voxel-based morphometry (VBM) and resting-state functional connectivity (rsFC) analysis to investigate the relationship between the ability of object and spatial working memory (WM), and regional gray matter density (GMD), as well as intrinsic functional connectivity. The VBM analysis showed a positive correlation between the individual difference of object WM and GMD in the right middle occipital gyrus (MOG) and the left superior temporal gyrus (STG), which are responsible for coding object information and processing the shape of an object. The individual difference of the spatial WM was positively related to GMD in the right middle frontal gyrus (MFG) located in the dorsolateral prefrontal cortex (dlPFC), which confirmed that it is an important region for memory stores and maintains WM spatial representations. Further functional connectivity analysis revealed that the individual difference of object WM was significantly correlated with the rsFC of right intraparietal sulcus (IPS) - left postcentral gyrus (PostCG)/right precentral gyrus (PreCG)/left Supplementary Motor Area (SMA). While the capacity of spatial WM was significantly associated with the FC strength of the left dlPFC - left precuneus, right dlPFC - right MFG, and the left superior frontal sulcus (SFS) - left SMA/ right inferior parietal lobe (IPL). Our findings suggest that object WM is associated with the structure and functional organization of the brain regions involved in the ventral pathway (occipital - temporal regions) and the capacity of spatial WM is related to the dorsal pathway (frontal - parietal regions).
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