Evidence map›Paper›PMID 31379471›Full record

ArticleCardiopulmonary physical therapy journal2018

Six-Minute Walk Test as a Predictive Measure of Exercise Capacity in Adults with Type 2 Diabetes.

Eric Nolen-Doerr, Kent Crick, Chandan Saha, Mary de Groot, Yegan Pillay, Jay H Shubrook, David Donley, W Guyton Hornsby

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Article in Cardiopulmonary physical therapy journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
  6. Measurement Properties of the Modified Incremental Step Test for Assessing Exercise Capacity in Individuals With Type 2 Diabetes.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  7. Article
  8. Comprehensive study of associated factors with Type 2 Diabetes in Mexico: protocol.Revista medica del Instituto Mexicano del Seguro Social · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eric Nolen-DoerrIndiana University, Department of Internal Medicine.
Kent CrickIndiana University School of Medicine, Diabetes Translational Research Center.
Chandan SahaIndiana University School of Medicine, Diabetes Translational Research Center.
Mary de GrootIndiana University School of Medicine, Diabetes Translational Research Center.
Yegan PillayOhio University.
Jay H ShubrookTouro University California, Primary Care Department Ohio University Heritage College of Osteopathic Medicine.
David DonleyWest Virginia University, Department of Human Performance - Exercise Physiology.
W Guyton HornsbyWest Virginia University, Department of Human Performance - Exercise Physiology.

Funding

Program ACTIVE II: Behavioral Depression Treatment for Type 2 DiabetesR18DK092765 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI DE GROOT, MARY K. · 2011 to 2015
$3.2M
NIDDK NIH HHS R18 DK092765
6 · The paper itself

Abstract

objectiveThe 6 Minute Walk Test (6MWT) is a measure that is routinely used to assess a response to treatment for cardiopulmonary diseases such as pulmonary fibrosis and congestive heart failure. The measure has never been verified as a valid measure of exercise capacity in the highly prevalent patient population of type 2 diabetes (T2DM). This study investigated the correlation between the 6MWT and graded exercise testing (GXT) in an effort to validate the 6MWT as a quality tool for assessing exercise capacity in adults with T2DM. RESEARCH DESIGN AND

methodThis is a secondary data analysis of Program ACTIVE II, a randomized controlled trial designed to assess the effectiveness of two behavioral interventions on depression and glycemic outcomes in adults with T2DM. The correlation of 6MWT and predicted VO2 max (PVO2M) using GXT was examined in a subsample of participants at the time of study enrollment and at post-intervention.

resultsPVO2M showed a significant correlation with 6MWT distance both at baseline (r=0.57, p=0.014) and post-intervention (r = 0.66, p = 0.037). The regression analysis of baseline data revealed that 6MWT distance alone explained 45% (F = 13.03, p = .0024) of the variability in PVO2M. When combined with the SF-12 physical health component score (PCS), 6MWT explained 66% (F = 13.62, p < .001) of the variance in PVO2M. After adjusting for PCS, 6MWT distance explained an additional 30% variability in PVO2M.

conclusionsFindings from this study indicate that the 6MWT and predicted exercise capacity are significantly correlated. The 6MWT can be used to estimate exercise capacity in adults with T2DM.

Identifiers

PMID31379471
PMCPMC6677537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.