ArticlePaediatrics & child health2019
Choosing medications wisely: Is it time to address paediatric polypharmacy?
Article in Paediatrics & child health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A Qualitative Study of Parent and Health Care Provider Perspectives on Polypharmacy in Children With Medical Complexity.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Article
- The role and perception of the caregiver in a specialized pediatric palliative care center in medicine preparation and administration: a survey study.Italian journal of pediatrics · 2024Article
- Polypharmacy in Children with Medical Complexity: A Cross-Sectional Study in a Pediatric Palliative Care Center.Children (Basel, Switzerland) · 2024Article
- Findings from an expert focus group on psychotropic medication deprescribing practices for children and youth with complex needs.Frontiers in child and adolescent psychiatry · 2024Article
- Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders.Children's health care : journal of the Association for the Care of Children's Health · 2024Article
- A coordinated approach for managing polypharmacy among children with medical complexity: rationale and design of the Pediatric Medication Therapy Management (pMTM) randomized controlled trial.BMC health services research · 2023Article
- Pharmacogenetic profiling via genome sequencing in children with medical complexity.Pediatric research · 2023Article
- Making Polypharmacy Safer for Children with Medical Complexity.The Journal of pediatrics · 2023Article
- Anticholinergic Medications and Parent-Reported Anticholinergic Symptoms in Neurologically Impaired Children.Journal of pain and symptom management · 2023Article
- Evaluation of rational prescribing in a hospital paediatric outpatient clinic in Nigeria.BMJ paediatrics open · 2022Observational
- Choosing Wisely in pediatric healthcare: A narrative review.Frontiers in pediatrics · 2022Review
- Medications Reconciled at Discharge Versus Admission Among Inpatients at a Children's Hospital.Hospital pediatrics · 2021Article
- Long-term use of antidepressants, mood stabilizers, and antipsychotics in pediatric patients with a focus on appropriate deprescribing.The mental health clinician · 2021Article
- Complexity of Medication Regimens for Children With Neurological Impairment.JAMA network open · 2021Article
- The Use of Antidepressants, Antipsychotics, and Stimulants in Youth Residential Care.Journal of child and adolescent psychopharmacology · 2021Article
- A whole of population retrospective observational study on the rates of polypharmacy in New Zealand 2014 to 2018 Polypharmacy in New Zealand: What is the current status?Health science reports · 2021Article
- Psychotropic Polypharmacy in the US Pediatric Population: A Methodologic Critique and Commentary.Frontiers in psychiatry · 2021Review
- Challenges of managing pediatric polypharmacy in a pediatric complex care program: A qualitative pilot study.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
There is a growing focus in the medical community on de-escalating medical treatments where appropriate; however, specific efforts to reduce medication burden in patients with polypharmacy has largely been targeted toward adult populations. Polypharmacy increases the risk of adverse drug reactions in children, and that risk may be further increased by the use of off-label drugs. The paediatric prescribing community should explore pharmacovigilance strategies and deprescription initiatives that prioritize patients with polypharmacy. Currently, best practices may be extrapolated from the adult literature, including medication review algorithms and patient education tools. Enhancing access to nonpharmacological modalities to address child and youth mental health may mitigate psychotropic polypharmacy. The aim of these initiatives should be to improve patient outcomes and experiences by avoiding adverse drug events and drug-drug interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.