ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2019
Clinical Integration of Automated Processing for Brain Quantitative Susceptibility Mapping: Multi-Site Reproducibility and Single-Site Robustness.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- An external reference to enable quantitative susceptibility mapping (QSM) in absolute terms: theoretical considerations, simulations, and experimental evaluation.Magma (New York, N.Y.) · 2026Article
- Quantitative Susceptibility Mapping of the Cervical Spinal Cord at 3T and Application to Multiple Sclerosis.NMR in biomedicine · 2026Article
- Hybrid Tau-PET/MRI study: Quantitative susceptibility mapping in progressive supranuclear palsy and its correlation with Tau-PET.European journal of nuclear medicine and molecular imaging · 2026Article
- Repeatability of Susceptibility Source Separation Methods in Human Brain: A Single-Site Study at 3 T.NMR in biomedicine · 2026Article
- Comparing repeatability metrics for quantitative susceptibility mapping in the head and neck.Magma (New York, N.Y.) · 2025Article
- Sensitivity of Quantitative Susceptibility Mapping for Clinical Research in Deep Gray Matter.Human brain mapping · 2025Article
- Thalamic iron in multiple sclerosis: Waning support for the early-rise late-decline hypothesis.NeuroImage. Clinical · 2025Article
- Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson's disease.NPJ Parkinson's disease · 2024Article
- The sequence of regional structural disconnectivity due to multiple sclerosis lesions.Brain communications · 2023Article
- Brain oxygen extraction and neural tissue susceptibility are associated with cognitive impairment in older individuals.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Ironsmith: An automated pipeline for QSM-based data analyses.NeuroImage · 2022Article
- Structural disconnectivity from paramagnetic rim lesions is related to disability in multiple sclerosis.Brain and behavior · 2021Article
- R2* and quantitative susceptibility mapping in deep gray matter of 498 healthy controls from 5 to 90 years.Human brain mapping · 2021Article
- Magnetic resonance quantitative susceptibility mapping in the evaluation of hepatic fibrosis in chronic liver disease: a feasibility study.Quantitative imaging in medicine and surgery · 2021Article
- Cerebral oxygen extraction fraction: Comparison of dual-gas challenge calibrated BOLD with CBF and challenge-free gradient echo QSM+qBOLD.Magnetic resonance in medicine · 2021Article
- [Reproducibility analysis of quantitative susceptibility mapping of cerebral subcortical nuclei in healthy adults].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Quantitative Susceptibility Mapping: MRI at 7T versus 3T.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020Article
- Initial Experience of Challenge-Free MRI-Based Oxygen Extraction Fraction Mapping of Ischemic Stroke at Various Stages: Comparison With Perfusion and Diffusion Mapping.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
background and purposeQuantitative susceptibility mapping (QSM) of the brain has become highly reproducible and has applications in an expanding array of diseases. To translate QSM from bench to bedside, it is important to automate its reconstruction immediately after data acquisition. In this work, a server system that automatically reconstructs QSM and exchange images with the scanner using the DICOM standard is demonstrated using a multi-site, multi-vendor reproducibility study and a large, single-site, multi-scanner image quality review study in a clinical environment.
methodsA single healthy subject was scanned with a 3D multi-echo gradient echo sequence at nine sites around the world using scanners from three manufacturers. A high-resolution (HiRes, .5 × .5 × 1 mm
resultsReconstruction times using a GPU were 29 ± 22 seconds (StdRes) and 55 ± 39 seconds (HiRes). ROI standard deviation across sites was below 24 ppb (StdRes) and 17 ppb (HiRes). Correlations between ROI averages across sites were on average .92 (StdRes) and .96 (HiRes). Image quality review of 873 consecutive patients revealed diagnostic or excellent image quality in 96% of patients.
conclusionOnline QSM reconstruction for a variety of sites and scanner platforms with low cross-site ROI standard deviation is demonstrated. Image quality review revealed diagnostic or excellent image quality in 96% of 873 patients.
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