Evidence map›Paper›PMID 31378813›Full record

ArticleInternational journal of epidemiology2020

Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol).

Suzette J Bielinski, Jennifer L St Sauver, Janet E Olson, Nicholas B Larson, John L Black, Steven E Scherer, Matthew E Bernard, Eric Boerwinkle, Bijan J Borah, Pedro J Caraballo and 38 more

Abstract read
In one paragraph

Article in International journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of real-world evidence on the clinical relevance, characterization, and utility ofJournal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Implementation of Pharmacogenetics in the United Kingdom.Handbook of experimental pharmacology · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Targeted Genotyping in Clinical Pharmacogenomics: What Is Missing?The Journal of molecular diagnostics : JMD · 2022
    Article
  18. Article
  19. Review
  20. Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Suzette J BielinskiDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jennifer L St SauverDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Janet E OlsonDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Nicholas B LarsonDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
John L BlackCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Steven E SchererHuman Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Matthew E BernardDepartment of Family Medicine, Mayo Clinic, Rochester, MN, USA.
Eric BoerwinkleHuman Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Bijan J BorahRobert D and Patricia E Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Pedro J CaraballoDivision of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Timothy B CurryCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
HarshaVardhan DoddapaneniHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Christine M FormeaDepartment of Pharmacy, Mayo Clinic, Rochester, MN, USA.
Robert R FreimuthDivision of Digital Health Sciences, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Richard A GibbsHuman Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Jyothsna GiriCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Matthew A HathcockDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jianhong HuHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Debra J JacobsonDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Leila A JonesCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Sara KallaHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Tyler H KoepOneOme, LLC, Minneapolis, MN, USA.
Viktoriya KorchinaHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Christie L KovarHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Sandra LeeHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Hongfang LiuDivision of Digital Health Sciences, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Eric T MateyCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Michaela E McGreeDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Tammy M McAllisterCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Ann M MoyerDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Donna M MuznyHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Wayne T NicholsonDepartment of Anesthesia and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Lance J OyenDepartment of Pharmacy, Mayo Clinic, Rochester, MN, USA.
Xiang QinHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Ritika RajHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Véronique L RogerDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Carolyn R Rohrer VitekCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Jason L RossOneOme, LLC, Minneapolis, MN, USA.
Richard R SharpCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Paul Y TakahashiDivision of Community Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Eric VennerHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Kimberly WalkerHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Liwei WangDivision of Digital Health Sciences, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Qiaoyan WangHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Jessica A WrightCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Tsung-Jung WuHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Liewei WangCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Richard M WeinshilboumCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.

Funding

Genomic Basis of Susceptibility to COVID-19 Infection and its ComplicationsU01HG006379 · NHGRI · MAYO CLINIC ROCHESTER · PI Richard R. Sharp · 2011 to 2026
$16.5M
Pharmacogenetics of Phase II Drug Metabolizing EnzymesU19GM061388 · NIGMS · MAYO CLINIC ROCHESTER · PI WEINSHILBOUM, RICHARD M. · 2010 to 2014
$15.8M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
INHERITED VARIATIONS IN DRUG-METABOLIZING ENZYMESR01GM028157 · NIGMS · MAYO CLINIC ROCHESTER · PI WEINSHILBOUM, RICHARD M. · 1985 to 2019
$6.9M
Pharmacogenomics of Breast Cancer Adjuvant ChemotherapyU01HG005137 · NHGRI · MAYO CLINIC ROCHESTER · PI WEINSHILBOUM, RICHARD M. · 2009 to 2011
$2.1M
Pharmacogenomic regulation of CYP transcription by TSPYL genesR01GM125633 · NIGMS · MAYO CLINIC ROCHESTER · PI WANG, LIEWEI · 2018 to 2021
$1.2M
NHGRI NIH HHS U01 HG005137NHGRI NIH HHS U01 HG006379NIA NIH HHS R01 AG034676NIGMS NIH HHS R01 GM028157NIGMS NIH HHS R01 GM125633NIGMS NIH HHS U19 GM061388
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical ProtocolsGenomicsPharmacogeneticsCohort StudiesFemaleHumansMalePrecision Medicine

Identifiers

PMID31378813
PMCPMC7124480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.