ReviewBritish journal of cancer2019
Challenges of international oncology trial collaboration-a call to action.
Review in British journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions.BMJ open · 2024Pooled it
- Overcoming Logistical Barriers to Conducting Collaborative Clinical Research Between a High-Income Country and a Low- and Middle-Income Country.JCO global oncology · 2026Article
- Global clinical trial activity in metastatic castration-resistant prostate cancer from January 2020 to March 2026: a landscape analysis.Frontiers in oncology · 2026Review
- Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment.Chemistry & biodiversity · 2025Review
- Review
- Mind the (research) gap: a retrospective observational study on the utilization of new medical technologies and related research activities in German hospitals.Health research policy and systems · 2025Observational
- Analyzing collaborations in clinical trials in Korea using association rule mining.Translational and clinical pharmacology · 2024Article
- A systematic review on the epidemiology and treatment options of multiple Myeloma in Asia.Heliyon · 2024Article
- Advancements in Immunotherapy for Breast Cancer: Mechanisms, Efficacy, and Future Directions.Cureus · 2024Review
- Considerations for establishing and maintaining international research collaboration: the example of chemotherapy-induced peripheral neurotoxicity (CIPN)-a white paper.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Review
- Children's Oncology Group blueprint for research: Acute lymphoblastic leukemia.Pediatric blood & cancer · 2023Article
- Landscape of clinical trials across the pancreatic cancer care continuum: an Australian perspective.The Medical journal of Australia · 2022Article
- Barriers and facilitators to cancer clinical trial enrollment and participation among rural populations: a scoping review protocol.JBI evidence synthesis · 2022Article
- Knowledge and attitudes towards clinical trials among women with ovarian cancer: results of the ACTO study.Journal of ovarian research · 2022Observational
- Innovation in cancer therapeutics and regulatory perspectives.Medical oncology (Northwood, London, England) · 2022Review
- Timelines to initiate a phase III trial across the globe: a sub-analysis of the APHINITY trial.Ecancermedicalscience · 2022Article
- Strategy management in collaborative clinical research partnerships.Contemporary clinical trials communications · 2021Article
- Drivers of Start-Up Delays in Global Randomized Clinical Trials.Therapeutic innovation & regulatory science · 2021Article
- Review
- Exploring the changing geographical pattern of international scientific collaborations through the prism of cities.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
International collaboration in oncology trials has the potential to enhance clinical trial activity by expediting the recruitment of large patient populations, testing treatments in diverse populations and facilitating the study of rare tumours or specific molecular subtypes. However, a number of challenges continue to hinder the efficient and productive conduct of both commercial and non-commercial international clinical trials. These challenges include complex and burdensome regulatory requirements, the high cost of conducting trials, and logistical challenges associated with ethics review, drug supply and biospecimen collection and management. We propose solutions to promote oncology trial collaboration, such as regulatory reform, harmonisation of trial initiation and management processes and greater recognition and funding of academic (non-commercial) clinical trials. It is only through coordinated effort and leadership from researchers, regulators and those responsible for health systems that the full potential of international trial collaboration can be realised.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.