Evidence map›Paper›PMID 31378213›Full record

ArticleParasitology2019

Mucosal microbial parasites/symbionts in health and disease: an integrative overview.

Robert P Hirt

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Journal of medical microbiology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Conservation of parasites: A primer.International journal for parasitology. Parasites and wildlife · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Shifts in the Fecal Microbial Community ofFrontiers in microbiology · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Robert P HirtInstitute for Cell and Molecular Biosciences,Faculty of Medical Sciences,Newcastle University,Newcastle upon Tyne, NE2 4HH,UK.ORCID 0000-0002-3760-9958
Newcastle University · GB

Funding

Wellcome Trust 045702Wellcome Trust 060068
6 · The paper itself

Abstract

Microbial parasites adapted to thrive at mammalian mucosal surfaces have evolved multiple times from phylogenetically distant lineages into various extracellular and intracellular life styles. Their symbiotic relationships can range from commensalism to parasitism and more recently some host-parasites interactions are thought to have evolved into mutualistic associations too. It is increasingly appreciated that this diversity of symbiotic outcomes is the product of a complex network of parasites-microbiota-host interactions. Refinement and broader use of DNA based detection techniques are providing increasing evidence of how common some mucosal microbial parasites are and their host range, with some species being able to swap hosts, including from farm and pet animals to humans. A selection of examples will illustrate the zoonotic potential for a number of microbial parasites and how some species can be either disruptive or beneficial nodes in the complex networks of host-microbe interactions disrupting or maintaining mucosal homoeostasis. It will be argued that mucosal microbial parasitic diversity will represent an important resource to help us dissect through comparative studies the role of host-microbe interactions in both human health and disease.

Indexed as

Host Microbial InteractionsHost-Parasite InteractionsSymbiosisAdaptive ImmunityAnimalsHumansImmunity, InnateMucous MembraneParasitic DiseasesPhylogenyZoonosesBacteriaextracellular and intracellular parasitesinnate and adaptive immune responsesmicrobiotamucosaparasitic protistsparasitic protozoapathobiontsviruses

Identifiers

PMID31378213
PMCPMC6817359
OpenAlexW2965606578

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.