Evidence map›Paper›PMID 31378106›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

Estrogen Receptor-β Mediates Estradiol-Induced Pregnancy-Specific Uterine Artery Endothelial Cell Angiotensin Type-2 Receptor Expression.

Jay S Mishra, Gigi M Te Riele, Qian-Rong Qi, Thomas J Lechuga, Kathirvel Gopalakrishnan, Dong-Bao Chen, Sathish Kumar

Open access · greenAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. The angiotensin II type 2 receptor attenuates aging-associated arterial stiffness in female mice.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Gestational Intermittent Hypoxia Impairs ATJournal of biotechnology and biomedicine · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Angiotensin ATPharmacological reviews · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jay S MishraFrom the Department of Comparative Biosciences, School of Veterinary Medicine (J.S.M., G.M.t.R., K.G., S.K.), University of Wisconsin-Madison.
Gigi M Te RieleFrom the Department of Comparative Biosciences, School of Veterinary Medicine (J.S.M., G.M.t.R., K.G., S.K.), University of Wisconsin-Madison.
Qian-Rong QiDepartment of Obstetrics and Gynecology, University of California-Irvine (Q.-R.Q., T.J.L., D.-b.C.).
Thomas J LechugaDepartment of Obstetrics and Gynecology, University of California-Irvine (Q.-R.Q., T.J.L., D.-b.C.).
Kathirvel GopalakrishnanFrom the Department of Comparative Biosciences, School of Veterinary Medicine (J.S.M., G.M.t.R., K.G., S.K.), University of Wisconsin-Madison.
Dong-Bao ChenDepartment of Obstetrics and Gynecology, University of California-Irvine (Q.-R.Q., T.J.L., D.-b.C.).
Sathish KumarFrom the Department of Comparative Biosciences, School of Veterinary Medicine (J.S.M., G.M.t.R., K.G., S.K.), University of Wisconsin-Madison.
University of Wisconsin–Madison · US

Funding

Actions of Estrogen on Uterine Artery EndotheliumR01HL070562 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, DONGBAO · 2001 to 2025
$6.3M
Sex-specific fetal programming of adult vascular dysfunction and hypertensionR01HL119869 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI KUMAR, SATHISH · 2013 to 2017
$1.9M
Vascular AT2R expression and function during pregnancyR01HL134779 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI KUMAR, SATHISH · 2017 to 2020
$1.5M
Estrogen and Endothelial Protein NitrosylationR21HL098746 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, DONGBAO · 2010 to 2011
$421k
Maternal Androgen Excess: Vascular and Placental Function and Fetal ConsequencesR03HD069750 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUMAR, SATHISH · 2011 to 2012
$153k
NHLBI NIH HHS R01 HL070562NHLBI NIH HHS R01 HL119869NHLBI NIH HHS R01 HL134779NHLBI NIH HHS R21 HL098746NICHD NIH HHS R03 HD069750
6 · The paper itself

Abstract

The pregnancy-augmented uterine vasodilation is linked to increased AT

Indexed as

AnimalsEndothelial CellsEndothelium, VascularEstradiolEstrogen Receptor betaFemalePregnancyRatsReceptor, Angiotensin, Type 2Up-RegulationUterine ArteryEstradiolEstrogen Receptor betaReceptor, Angiotensin, Type 2endothelial cellsestradiolestrogenspregnancyuterine artery

Identifiers

PMID31378106
PMCPMC6739159
OpenAlexW2966730346

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.