Evidence map›Paper›PMID 31377959›Full record

ArticlePurinergic signalling2019

Onset kinetics of noise-induced purinergic adaptation of the 'cochlear amplifier'.

Jennie M E Cederholm, Allen F Ryan, Gary D Housley

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Purinergic signalling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Medial Olivocochlear Efferent Modulation of Cochlear Micromechanics Requires P2X4 Receptor in Outer Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Review
  5. Whole Stimulus DPOAE Analysis.AIP conference proceedings · 2024
    Article
  6. Article
  7. Purinergic Signalling in the Cochlea.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jennie M E CederholmTranslational Neuroscience Facility and Department of Physiology, School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia.
Allen F RyanDepartments of Surgery and Neurosciences, University of California San Diego, La Jolla, CA, USA.
Gary D HousleyTranslational Neuroscience Facility and Department of Physiology, School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia. g.housley@unsw.edu.au.ORCID 0000-0002-8413-588X
UNSW Sydney · AUUnited States Department of Veterans Affairs · US

Funding

BLRD VA I01 BX001205RRD VA I01 RX000977VA BX001205VA RX000977
6 · The paper itself

Abstract

A major component of slowly reversible hearing loss which develops with sustained exposure to noise has been attributed to release of ATP in the cochlea activating P2X

Indexed as

Acoustic StimulationAdaptation, PhysiologicalAnimalsEvoked Potentials, Auditory, Brain StemHair Cells, Auditory, OuterMiceMice, Inbred C57BLNoiseOtoacoustic Emissions, SpontaneousAuditory brainstem responseDistortion product otoacoustic emissionMouseNoise-induced hearing lossP2X2 receptorTemporary threshold shift

Identifiers

PMID31377959
PMCPMC6737159
OpenAlexW2964525271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.