Evidence map›Paper›PMID 31377952›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2019

Allopregnanolone reversion of estrogen and progesterone memory impairment: interplay with serotonin release.

C Escudero, F Giuliani, M Mulle Bernedo, Roberto Yunes, R Cabrera

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C EscuderoInstituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza (IMBECU-CONICET), Huarpes 630, 5500, Mendoza, Argentina.
F GiulianiInstituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza (IMBECU-CONICET), Huarpes 630, 5500, Mendoza, Argentina.
M Mulle BernedoInstituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza (IMBECU-CONICET), Huarpes 630, 5500, Mendoza, Argentina.
Roberto YunesInstituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza (IMBECU-CONICET), Huarpes 630, 5500, Mendoza, Argentina. roberto.yunes@um.edu.ar.ORCID 0000-0001-7325-953X
R CabreraInstituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza (IMBECU-CONICET), Huarpes 630, 5500, Mendoza, Argentina.
University of Mendoza · AR

Funding

CONICET PIP 11220100100126/11University of Mendoza 113/07
6 · The paper itself

Abstract

Previously, we found out that in ovariectomized female rats, estrogen and progesterone produce a memory deficit which is reverted by the intrahippocampal administration of allopregnanolone. Here, we study the possible interplay between allopregnanolone and hippocampal serotonergic activity. Ovariectomized rats injected subcutaneously with estrogen and progesterone were subsequently injected in the dorsal hippocampus with vehicle, allopregnanolone alone or allopregnanolone shortly after 8OH-DPAT, a predominantly 5HT

Indexed as

AnimalsEstrogensFemaleLocomotionMemory DisordersOvariectomyPregnanoloneProgesteroneRatsRats, Sprague-DawleySerotoninSerotonin Receptor AgonistsEstrogensPregnanoloneProgesteroneSerotoninSerotonin Receptor AgonistsAllopregnanoloneEstrogenMemoryProgesteroneSerotonin

Identifiers

PMID31377952
OpenAlexW2965061036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.