Evidence map›Paper›PMID 31377894›Full record

ArticleAIDS and behavior2019

Attitudes Toward Long-Term Use of Antiretroviral Therapy Among HIV-Infected Pregnant Women in Moshi, Tanzania: A Longitudinal Study.

Linda Minja, Cody Cichowitz, Brandon A Knettel, Michael J Mahande, Godfrey Kisigo, Elizabeth T Knippler, James S Ngocho, Blandina T Mmbaga, Melissa H Watt

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Linda MinjaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Cody CichowitzMassachusetts General Hospital, Department of Medicine, Center for Global Health, Boston, USA.
Brandon A KnettelDuke Global Health Institute, Duke University, 310 Trent Drive, Box 90519, Durham, NC, 27708, USA.
Michael J MahandeKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Godfrey KisigoKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Elizabeth T KnipplerDuke Global Health Institute, Duke University, 310 Trent Drive, Box 90519, Durham, NC, 27708, USA.
James S NgochoKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Blandina T MmbagaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Melissa H WattDuke Global Health Institute, Duke University, 310 Trent Drive, Box 90519, Durham, NC, 27708, USA. Melissa.Watt@duke.edu.
Kilimanjaro Christian Medical Centre · TZDuke Institute for Health Innovation · USDuke University · USCenter for Global Health · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
Sociobehavioral Sciences Research to Improve Care for HIV Infection in TanzaniaD43TW009595 · FIC · KILIMANJARO CHRISTIAN MEDICAL CENTRE · PI Blandina Theophil Mmbaga · 2013 to 2026
$4.2M
A stigma reduction intervention at time of entry into antenatal care to improve PMTCT services in TanzaniaR21TW011053 · FIC · UNIVERSITY OF UTAH · PI MMBAGA, BLANDINA THEOPHIL, WATT, MELISSA H · 2018 to 2019
$424k
Postpartum HIV care engagement in the context of Option B+ in TanzaniaR21AI124344 · NIAID · DUKE UNIVERSITY · PI MMBAGA, BLANDINA THEOPHIL, WATT, MELISSA H · 2016 to 2017
$314k
FIC NIH HHS D43 TW009595FIC NIH HHS R21 TW011053Fogarty International Center (US) D43TW009595Fogarty International Center (US) R21TW011053NIAID NIH HHS P30 AI064518NIAID NIH HHS R21 AI124344
6 · The paper itself

Abstract

Adherence to antiretroviral therapy (ART) during pregnancy and the postpartum period is necessary to prevent vertical HIV transmission and to secure the long-term health of an HIV-infected woman. Health behavior theory suggests that patients' attitudes towards medication can predict their medication-taking behaviour. This study sought to understand how women's attitudes towards ART changes between the pregnancy and postpartum periods, and the factors associated with these attitudes. The study enrolled 200 pregnant women living with HIV. Structured surveys were administered during pregnancy and at three and 6 months postpartum. Overall, attitudes towards ART were stable over time. More positive attitudes towards ART were associated with HIV acceptance, lower levels of depression, and lower levels of shame. Counselling interventions are needed to help HIV-infected women accept their status and reduce shameful emotions. Depression screening and treatment should be integrated into PMTCT services. This study emphasizes the importance of early attention to attitudes towards ART, in order to establish a trajectory of sustained care engagement.

Indexed as

Health BehaviorAdultAnti-Retroviral AgentsCounselingDrug MonitoringFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalLongitudinal StudiesMedication AdherencePostpartum PeriodPregnancyPregnancy Complications, InfectiousPregnant PeopleTanzaniaAnti-Retroviral AgentsAdherenceHIV/AIDSOption B+Prevention of mother-to-child transmission (PMTCT)Tanzania

Identifiers

PMID31377894
PMCPMC7467083
OpenAlexW2964761255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.