Evidence map›Paper›PMID 31377882›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2019

In vitro study of the cytotoxicity of thymoquinone/curcumin fluorescent liposomes.

Heba Mohamed Fahmy

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Heba Mohamed FahmyBiophysics Department, Faculty of Science, Cairo University, 16 El Zafer Street, Haram, Giza, Egypt. heba_moh_fahmi@yahoo.com.ORCID 0000-0001-8689-1198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, thymoquinone-loaded liposomes (Lip (TQ)), curcumin-encapsulated liposome (Lip (CUR)), and thymoquinone/curcumin-encapsulated liposome (Lip (TQ + CUR)) in addition to rhodamine-labeled thymoquinone/curcumin liposome (Lip (TQ + CUR + ROD)) were prepared with encapsulation efficiency exceeding 99%. The aim of the present study was to evaluate the effect of the different prepared formulations either labeled with the fluorescent dye (rhodamine B) or not on A549 lung cancer cells. Cytotoxicity of different formulations was assessed by MTT assay. Proliferation of A549 cells was significantly inhibited by the different formulations in a concentration-dependent manner in 72 h. The Lip (TQ + CUR + ROD) formulation demonstrated the lowest IC

Indexed as

A549 CellsAntineoplastic Agents, PhytogenicBenzoquinonesCell SurvivalComet AssayCurcuminDNA DamageDose-Response Relationship, DrugDrug CarriersDrug CompoundingHumansLiposomesMicroscopy, FluorescenceOxidative StressSurface PropertiesAntineoplastic Agents, PhytogenicBenzoquinonesCurcuminDrug CarriersLiposomesthymoquinoneComet assayCurcuminFluorescent microscopeLiposomeRhodamine BThymoquinone

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.