Evidence map›Paper›PMID 31377821›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Staging FDG PET-CT changes management in patients with gastric adenocarcinoma who are eligible for radical treatment.

Karen D Bosch, Sugama Chicklore, Gary J Cook, Andrew R Davies, Mark Kelly, James A Gossage, Cara R Baker

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
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  14. The feasibility of ultralow-activityAnnals of nuclear medicine · 2022
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  15. Review
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  17. Article
  18. Frontiers in oncology · 2022
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  19. Article
  20. Head-to-head comparison of [European journal of nuclear medicine and molecular imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karen D BoschDepartment of Upper GI Surgery, Guy's & St Thomas' Hospital, London, SE1 7EH, UK. karen.bosch@nhs.net.ORCID 0000-0001-9196-2923
Sugama ChickloreDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, SE1 7EH, UK.
Gary J CookDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, SE1 7EH, UK.
Andrew R DaviesDepartment of Upper GI Surgery, Guy's & St Thomas' Hospital, London, SE1 7EH, UK.
Mark KellyDepartment of Upper GI Surgery, Guy's & St Thomas' Hospital, London, SE1 7EH, UK.
James A GossageDepartment of Upper GI Surgery, Guy's & St Thomas' Hospital, London, SE1 7EH, UK.
Cara R BakerDepartment of Upper GI Surgery, Guy's & St Thomas' Hospital, London, SE1 7EH, UK.
St Thomas' Hospital · GB

Funding

Cancer Research UK 16463Cancer Research UK A16463Wellcome Trust 203148Wellcome Trust 203148/Z/16/Z
6 · The paper itself

Abstract

aim18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) is valuable in the management of patients with oesophageal cancer, but a role in gastric cancer staging is debated. Our aim was to review the role of FDG PET-CT in a large gastric cancer cohort in a tertiary UK centre.

methodsWe retrospectively reviewed data from 330 patients presenting with gastric adenocarcinoma between March 2014 and December 2016 of whom 105 underwent pre-treatment staging FDG PET-CT scans. FDG PET-CT scans were graded qualitatively and quantitatively (SUV

resultsOf the 105 patients (74 M, median age 73 years) 86% of primary tumours were metabolically active (uptake greater than normal stomach) on FDG PET-CT [41/44 (93%) of the intestinal histological subtype (SUV

conclusionFDG PET-CT provides new information in a clinically useful proportion of patients, which leads to changes in treatment strategy, most frequently by detecting previously unidentified metastases, particularly in those with intestinal-type tumours.

Indexed as

AdenocarcinomaStomach NeoplasmsAgedFluorodeoxyglucose F18HumansNeoplasm StagingPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesSensitivity and SpecificityFluorodeoxyglucose F18RadiopharmaceuticalsCancer stagingGastric cancerMetastasesPET-CT

Identifiers

PMID31377821
PMCPMC7075833
OpenAlexW2965854082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.