Evidence map›Paper›PMID 31377752›Full record

ReviewPediatric research2020

Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: big data to the forefront.

Navin Kumar, Gangaram Akangire, Brynne Sullivan, Karen Fairchild, Venkatesh Sampath

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05243667 unknown statusnot on this mapstarted 2021, after this paper: background citation

Research on the Early Warning Model of Children Asthma Acute Attack Based on Wearable Wrist Smart Device of Huami

Typeobservational_patient_registrySponsorGuangzhou Institute of Respiratory DiseaseRan2021 to 2024Enrolled200ConditionsAsthma in ChildrenArmsWearable wrist Smart Device of Huami
NCT05245747 completednot on this mapstarted 2022, after this paper: background citation

Vitls Feasibility Physiologic Monitoring

TypeobservationalSponsorChildren's Mercy Hospital Kansas CityRan2022 to 2023Enrolled20ConditionsVital Signs, Pediatrics, Remote MonitoringArmsVitls Tego Device
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Navin KumarDivision of Neonatology, Hurley Medical Center, Flint, MI, USA.
Gangaram AkangireDivision of Neonatology, Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO, USA.
Brynne SullivanDivision of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.
Karen FairchildDivision of Neonatology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.
Venkatesh SampathDivision of Neonatology, Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO, USA. vsampath@cmh.edu.
Children's Mercy Hospital · USUniversity of Virginia · USHurley Medical Center · US

Funding

Predictive Informatics Monitoring in the Neonatal Intensive Care UnitR01HD072071 · NICHD · UNIVERSITY OF VIRGINIA · PI KAREN D FAIRCHILD, Brynne Archer Sullivan · 2014 to 2026
$7.6M
NICHD NIH HHS R01 HD072071
6 · The paper itself

Abstract

In the neonatal intensive care unit (NICU), heart rate, respiratory rate, and oxygen saturation are vital signs (VS) that are continuously monitored in infants, while blood pressure is often monitored continuously immediately after birth, or during critical illness. Although changes in VS can reflect infant physiology or circadian rhythms, persistent deviations in absolute values or complex changes in variability can indicate acute or chronic pathology. Recent studies demonstrate that analysis of continuous VS trends can predict sepsis, necrotizing enterocolitis, brain injury, bronchopulmonary dysplasia, cardiorespiratory decompensation, and mortality. Subtle changes in continuous VS patterns may not be discerned even by experienced clinicians reviewing spot VS data or VS trends captured in the monitor. In contrast, objective analysis of continuous VS data can improve neonatal outcomes by allowing heightened vigilance or preemptive interventions. In this review, we provide an overview of the studies that have used continuous analysis of single or multiple VS, their interactions, and combined VS and clinical analytic tools, to predict or detect neonatal pathophysiology. We make the case that big-data analytics are promising, and with continued improvements, can become a powerful tool to mitigate neonatal diseases in the twenty-first century.

Indexed as

Big DataHemodynamic MonitoringHemodynamicsIntensive Care Units, NeonatalOximetryVital SignsBirth WeightBlood PressureGestational AgeHeart RateHumansInfant, Extremely PrematureInfant, Low Birth WeightInfant, NewbornInfant, Newborn, DiseasesOxygenOxygen

Identifiers

PMID31377752
PMCPMC6962536
OpenAlexW2966860700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.